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Found 78 clinical trials
Sentinel Node Localization and Staging With Low Dose Superparamagnetic Iron Oxide (MAGSNOW)

Sentinel lymph node (SLN) status is pivotal for treatment decisions in breast cancer patients. The dual technique with Technetium99m (Tc99) and blue dye (BD) is yet the current routine for SLN detection. However, the same reliability has been presented by superparamagnetic iron oxide nanoparticles (SPIO). The aim of this study …

sentinel node
sentinel lymph node biopsy
breast-conserving surgery
  • 0 views
  • 10 May, 2022
  • 1 location
Axillary Staging in Early Breast Cancer: SNB vs PET/MRI

The gold standard of surgical treatment for patients with early breast cancer (BC) is breast conservation and sentinel node biopsy (SNB). Ongoing randomized trials are evaluating to omit surgery at all when axillary imaging is negative. However, the available diagnostic tools still have several limitations in accuracy. Combining the specificity …

mastectomy
sentinel node
breast-conserving surgery
  • 0 views
  • 04 Oct, 2022
  • 1 location
Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer

This phase II trial investigates the safety of delivering a part (boost) of radiation treatment before breast surgery in treating patients with breast cancer that has not spread to other places in the body (non-metastatic). Radiation therapy uses high energy photons/electrons to kill tumor cells and shrink tumors. Delivering a …

  • 0 views
  • 04 Oct, 2022
  • 3 locations
Patient's Choice in the Reduction of Their Treatment in Women Over 70 Year With Breast Cancer

Standard treatment for women with early breast cancer (HR+, HER2-, T1N0) consists of the removal of the tumor from the breast by surgery with or without chemotherapy, followed by a whole-breast radiation therapy (usually one radiation treatment a day, five days a week, for 3 to 6 weeks) In some …

HER2
erbb2
  • 0 views
  • 26 Oct, 2021
  • 1 location
Minimal Invasive Breast Cancer Excision Using Vacuum Assisted Biopsy Under Ultrasound Guidance

This study will assess whether it is feasible to remove small breast cancers completely using the Vacuum Assisted Biopsy (VAB) system System under Ultrasound guidance.

sentinel node
carcinoma
breast-conserving surgery
magnetic resonance imaging of breast
lumpectomy
  • 0 views
  • 27 Sep, 2021
  • 1 location
Real-time Intraoperative Breast Cancer Visualization for Margin Assessment

The investigators' preclinical data have demonstrated the feasibility of fluorescence-guided tumor resection by Cancer Vision Goggles (CVG) with LS301 in animal models. In this study, the investigators will conduct intraoperative imaging procedures that have minimal interference with ongoing surgery. The underlying hypothesis is that the accurate detection of all cancer …

mastectomy
lumpectomy
  • 0 views
  • 07 Oct, 2022
  • 1 location
High Five (HiFi) Accelerated Partial Breast Irradiation Study

To establish the role of adjuvant multicatheter interstitial high-dose-rate brachytherapy in doubly accelerated and radiobiologically equivalent irradiation scheme of 5 x 5,4 Gy in 3 days of treatment (High Five, HiFi-APBI) compared to the adopted long-term standard of APBI realized in 4-5 days (7-8 x 4-4,3 Gy) in selected women …

ductal carcinoma in situ
erbb2
invasive carcinoma
ductal carcinoma
lobular carcinoma
  • 0 views
  • 10 Dec, 2021
  • 1 location
A Prospective, Multi-center, Randomized, Double-arm Trial to Determine the Impact of the SELENE System on Positive Margin Rates in Breast Conservation Surgery. (RCT)

This is a multi-center, randomized, two-arm study designed to measure the effectiveness of the SELENE system in reducing the number of unaddressed positive margins in breast lumpectomy procedures when used in addition to standard intraoperative margin assessment.

Accepts healthy volunteers
ductal carcinoma in situ
carcinoma in situ
carcinoma
ductal carcinoma
  • 1 views
  • 28 Oct, 2022
  • 7 locations
Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer

This is a prospective, registry study that will enroll all women with early stage breast cancer who will be treated with intraoperative radiotherapy (IORT) during breast-conserving surgery. The

breast cancer staging
breast-conserving surgery
  • 1 views
  • 25 Apr, 2022
  • 1 location
Patient Report Outcome-Reconstruction and Oncoplastic Cohort (PRO-ROC)

reconstruction or oncoplastic breast-conserving surgery (OBCS). The inclusion criteria are female breast cancer patients >18 years old, who will undergo breast reconstruction (BR) or OBCS. This cohort will

cancer
breast cancer
breast-conserving surgery
female breast
female breast cancer
  • 16 views
  • 13 Feb, 2022
  • 1 location