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Found 83 clinical trials
EXamining PErsonalised Radiation Therapy for Low-risk Early Breast Cancer (EXPERT)

This is a randomised, phase III, non-inferiority trial evaluating radiation therapy versus observation following breast conserving surgery and planned endocrine therapy in patients with stage I

  • 745 views
  • 13 Jul, 2022
  • 59 locations
Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years (HAI-5-III)

This study will evaluate the effect of highly accelerated external beam radiotherapy (EBRT) in 5 fractions over 10 days compared to 15 fractions over 3 weeks for early as well as locally-advanced stage breast cancer. Primary endpoint will be chronic toxicity (breast deformation and retraction). Secondary endpoints are acute toxicity, …

  • 4 views
  • 25 Feb, 2022
  • 1 location
Sequential Neo-adjuvant Chemotherapy Followed by Capecitabine Vs. Conventional Adjuvant Chemotherapy in Breast Cancer (NACVCAC)

This study evaluates whether sequential neo-adjuvant chemotherapy plus surgery followed by Capecitabine could achieve additional benefits over traditional postoperative chemotherapy. In the study group, patients that do not achieve pathological complete response(pCR) will receive sequential neo-adjuvant chemotherapy followed by Capecitabine. In the control group, patients will be treated with postoperative …

renal function
carcinoma
breast cancer
capecitabine
cancer
  • 0 views
  • 25 Feb, 2022
  • 1 location
Hypofractionated Radiotherapy After Breast Conserving Surgery

The optimal dose and fractionation regimen for whole breast irradiation, whole breast and regional nodal irradiation, and postmastectomy radiotherapy remains unknown. The goal of this phase II randomized controlled trial is to determine whether the hypofractionated proton regimens proposed are non-inferior compared with standard fractionated proton radiotherapy and therefore worthy …

breast-conserving surgery
adjuvant chemotherapy
  • 7 views
  • 08 Nov, 2020
  • 2 locations
Simulating Outcomes From Breast Conserving Surgery Using 3D Surface Imaging

Most women with breast cancer are able to have an operation to remove the cancer while preserving the breast (breast conserving therapy, BCT). Whilst cancer control is the most important goal, appearance of the breast after surgery has been shown to affect the quality of a woman's life after treatment. …

cancer
breast-conserving surgery
breast cancer
  • 0 views
  • 25 Feb, 2022
  • 1 location
The Effect of Manual Lymph Drainage in the Treatment of Breast Edema

Breast conserving surgery (BCS) is widely used in the treatment of breast cancer. Breast edema can be seen frequently after BCS and radiotherapy applications. Breast edema affects quality of

  • 0 views
  • 15 Jun, 2022
  • 1 location
Outcomes of Breast Conservative Surgery for Post Chemotherapy Tumour Size After Response to Neoadjuvant Chemotherapy

tumor, NACT can convert patients who are candidates for mastectomy to breast-conserving surgery (BCS) candidates [7]. Furthermore, it has potential to reduce excision volumes in patients with large

Accepts healthy volunteers
  • 0 views
  • 20 Nov, 2021
  • 1 location
Digitally Distributed Yoga for Women Treated for Breast Cancer (DigiyogaCare)

Breast cancer is the most common cancer disease in women. As the prevalence of fatigue is high in this group it is motivated to find interventions that can reduce fatigue and render in an increased level of physical activity both during and after treatment. Yoga have shown effect on cancer …

  • 0 views
  • 11 Mar, 2022
  • 1 location
Hypofractionated Vs Conventional Fractionated Radiotherapy After Breast Conserving Surgery

patients after breast conserving surgery

invasive breast cancer
sentinel node
erbb2
metastasis
sentinel lymph node biopsy
  • 8 views
  • 12 Feb, 2022
  • 2 locations
Intraoperative Radiation Therapy in Treating Patients With Breast Cancer Undergoing Breast-Conserving Surgery

This phase IV trial studies the side effects of intraoperative radiation therapy and how well it works in treating patients with breast cancer undergoing breast-conserving surgery. Delivering

cancer
breast cancer staging
tumor cells
  • 101 views
  • 04 Oct, 2022
  • 27 locations