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Found 104 clinical trials
Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors

Post Mastectomy Pain Syndrome (PMPS) is a major complication of breast surgery responsible for depression and disability. The project consists of a prospective cohort on patients going

  • 0 views
  • 29 Jan, 2021
  • 2 locations
Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible

the radiation beam to the cancer and is currently given after breast surgery. A new combination of IMRT followed by hormone treatment given before surgery, may increase the possibility of breast

  • 0 views
  • 22 Jan, 2021
  • 1 location
Digital Breast Tomosynthesis (DBT) to Improve Assessment of Resection Margins in Invasive Breast Cancer

%-25% of primary invasive breast cancer patients will need a repeat surgery. Repeat breast surgery has been associated with higher surgical risks, poorer cosmetic outcome and increased psychological

carcinoma
ductal carcinoma
ductal carcinoma in situ
carcinoma in situ
breast-conserving surgery
  • 0 views
  • 25 Jan, 2021
  • 1 location
The Use of Lumbar Erector Spinae Plane Block for Hip Arthroplasty at the L4 Interspace

demonstrating its efficacy with a thoracic approach for analgesia in breast surgery and rib fractures.9 Only two case reports to date have demonstrated a lumbar approach to achieve analgesia for hip

analgesia
anesthesia
ropivacaine
joint arthroplasty
vomiting
  • 0 views
  • 27 Jan, 2021
  • 1 location
Prospective Study of the Prosigna Assay on Neoadjuvant Clinical Decision-making in Women With HR+/Her2- Breast Cancer

This research study is evaluating a genomic analysis called Predictor Analysis of Microarray 50 (PAM50, by Prosigna) as a tool to possibly guide the participant and the treating physician to choose the most personalized pre-operative treatment for breast cancer.

her2/neu-negative breast cancer
HER2
hormone therapy
endocrine therapy
erbb2
  • 0 views
  • 25 Jan, 2021
SENTINEL LYMPH NODE BIOPSY AFTER NEOADJUVANT CHEMOTHERAPY

Omitting axilary lymph node dissection (ALND) following SLNB with residual cancer in patients with locally advanced disease after neoadjuvan chemotherapy (NAC) is still controversial. In this study, the investigators evaluated factors affecting local recurrence and outcome in patients with locally advanced breast cancer (LABC), who underwent sentinel lymph node (SLN) …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Barriers Associated With Timely Adjuvant Chemotherapy Administration in Patients With Invasive Breast Cancer

This trial studies the barriers associated with timely chemotherapy given after surgery (adjuvant) in patients with invasive breast cancer. Meeting with patients and asking questions may help doctors to learn about factors that can cause delays in the start of chemotherapy after surgery in patients with breast cancer.

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  • 24 Jan, 2021
  • 1 location
Multimodal Perioperative Pain Management: ComfortSafe Program

Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical patients who receive opioid-sparing, multimodal anesthesia and pain management care as guided by the ComfortSafe Pyramid.

opioid
analgesia
anesthesia
propofol
analgesics
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies

The treatment of breast cancer is determined by its 'receptor (or signal) status'. Receptors are signals present on all cells and if abnormal can drive cancer growth. One of the signals that can drive breast cancer growth is the HER2 receptor/signal. One quarter of all breast cancers are found to …

breast cancer
HER2
targeted therapy
taxane
advanced breast cancer
  • 0 views
  • 23 Jan, 2021
  • 2 locations
Correlation of Preoperative Anxiety With Early Postoperativeognitive Dysfunction in Breast Cancer Patients

Breast cancer is the most common type of cancer in women. Anxiety and depression often accompany the treatment phase of oncology patients. Since both anxiety and depression are associated with increased inflammatory activity, these preoperative symptoms may predispose patients to the development of postoperative neurocognitive dysfunction. The aim of this …

  • 0 views
  • 28 Jan, 2021
  • 1 location