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Found 56 clinical trials
Pre-existing Factors Early Detection and Early Treatment of Breast Cancer Related Lymphedema

Breast-cancer related lymphoedema (BCRL) is a common phenomenon. Early diagnosis and treatment is very important to alter the normal progression of this disease. A threshold (>= 3% volume change) that recognizes subclinical lymphedema is promoted. When the lymphedema is diagnosed late, options for treatment are diminished as fibrous tissue is …

axillary lymph node dissection
sentinel node
sentinel lymph node biopsy
  • 11 views
  • 25 Jan, 2021
  • 1 location
Lymphaticovenous Anastomosis as Treatment for Lymphedema

The primary aim of this study is to investigate and test whether the use of combined indocyanine green (ICG) lymphography and ultra high frequency ultrasonography can correctly identify lymphatic vessels and venoles in close proximity to each other, for identification prior to lymphovenous anastomosis (LVA) surgery.

indocyanine green
cancer
breast cancer
primary cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

This clinical trial studies eliminating surgery and how well radiation therapy after systemic therapy works in treating patients with HER2 positive or triple negative breast cancer when image-guided biopsy shows no residual cancer. Patients then receive standard breast radiotherapy.

metastasis
metastatic disease
biomarker analysis
estrogen receptor
cancer
  • 32 views
  • 22 Sep, 2022
  • 5 locations
High Five (HiFi) Accelerated Partial Breast Irradiation Study

To establish the role of adjuvant multicatheter interstitial high-dose-rate brachytherapy in doubly accelerated and radiobiologically equivalent irradiation scheme of 5 x 5,4 Gy in 3 days of treatment (High Five, HiFi-APBI) compared to the adopted long-term standard of APBI realized in 4-5 days (7-8 x 4-4,3 Gy) in selected women …

ductal carcinoma in situ
her2/neu-positive breast cancer
carcinoma in situ
carcinoma
ductal carcinoma
  • 0 views
  • 10 Dec, 2021
  • 1 location
Quadratic Phenotypic Optimisation Platform (QPOP) Utilisation to Enhance Selection of Patient Therapy Through Patient Derived Organoids in Breast Cancer (QUEST)

Based on proof-of-concept study, the investigators hypothesise that the QPOP prediction model can be further extended into use in solid tumors. Using breast cancer as a model, the investigators intend to investigate the feasibility of QPOP as a clinical decision support platform to identify patient-specific drug combinations across a range …

advanced breast cancer
  • 0 views
  • 16 Mar, 2022
  • 1 location
Trastuzumab to Patients With Advanced Gastric Cancer With HER2 Positive Expression in CTC (GASTHER2)

BACKGROUND: Gastric cancer is one of the most common cancers and is one of the most deadly cancers. Most patients have advanced disease and should receive first-line trastuzumab-associated chemotherapy when the biopsy is positive for immunocytochemical expression and / or HER2 gene amplification. A study conducted by our group noted …

  • 0 views
  • 30 May, 2022
  • 1 location
Study on TIL for the Treatment of Advanced Breast Cancer

This study is to investigate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy (GC 101 TIL) in patients with advanced breast cancer. Autologous TILs are expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodepletion treatment with fludarabine and cyclophosphamide.

metastasis
advanced breast cancer
cyclophosphamide
  • 0 views
  • 04 Oct, 2022
  • 1 location
Registry Study of Pregnancy and Breast Cancer

An ambispective observational registry study of pregnancy and breast cancer

  • 0 views
  • 20 Nov, 2021
  • 28 locations
Mapping and Quantifying Lymphatic Drainage of the Arm's Alternate Pathway

Using indocyanine green (ICG) lymphography and lymphoscintigraphy with SPECT/CT imaging, the aim is to evaluate the anatomy of the lymphatic system pathway in two separate populations: healthy female volunteers and women with a history of breast cancer who did not develop lymphedema.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Patient Experiences With the COVID-19 Vaccination After Breast Cancer Treatment (LymphVAX)

This study aims to elicit patient experiences, choices, and side effects associated with the COVID-19 vaccine after breast cancer surgery. Lymph node swelling is a known and common side effect of both the Moderna and Pfizer COVID-19 vaccines. This is the body's normal reaction to the vaccine. It is worrisome …

breast cancer
cancer
cancer treatment
sentinel lymph node biopsy
  • 0 views
  • 21 Apr, 2022
  • 1 location