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Found 12 clinical trials
Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

Although the results obtained from ECOG E5194 cohort 1 (criteria: mammographically detected low- or intermediate-grade DCIS, measuring less than 2.5 cm with margins 3 mm) and RTOG 9804 trial (the same enrolled clinicopathological features to cohort 1 of ECOG E5194 trial) demonstrated that the 7-year ipsilateral breast tumor recurrence (IBTR) …

carcinoma in situ
radiotherapy to breast
cancer
breast cancer
estrogen receptor
  • 13 views
  • 14 Feb, 2022
  • 1 location
Effect of PACK Health Support Program on Patient Reported Outcomes in Patients With Breast Cancer

This trial studies the effect of an electronic health (eHealth) support program called PACK Health on patient reported health outcomes in patients with breast cancer. PACK Health monitors breast cancer patients' reported side effects and experience of care when receiving chemotherapy. Participating in the PACK Health coaching program may improve …

ductal carcinoma in situ
carcinoma
carcinoma in situ
cancer
invasive breast cancer
  • 4 views
  • 14 Feb, 2022
  • 1 location
Identifying and Caring for Individuals With Inherited Cancer Syndrome

This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and …

carcinoma
BRCA1
carcinoma in situ
cancer
breast cancer
  • 21 views
  • 23 Mar, 2022
  • 2 locations
Subzero and Scorpion Trial

This is a prospective single-institution pilot study examining the feasibility of performing ultrasound-guided cryoablation to completely ablate breast ductal carcinoma in situ (DCIS). The study

lobular carcinoma
carcinoma in situ
cancer
mammogram
breast cancer
  • 0 views
  • 11 Sep, 2021
  • 2 locations
A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

This phase Ib trial studies the side effects and best dose of a vaccine called H2NVAC before surgery in treating patients with HER2 expressing ductal carcinoma in situ. H2NVAC is a vaccine designed to stimulate specialized white blood cells in hopes of increasing immune response and protecting against breast cancer.

metastasis
neutrophil count
aromatase inhibitor
breast cancer
therapeutic conventional surgery
  • 6 views
  • 16 Feb, 2022
  • 2 locations
Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS

This prospective, one-arm study which will enroll participants with biopsy-proven DCIS scheduled for diagnostic breast MRI for preoperative staging/extent of disease evaluation as part of standard of care. Eligible participants will be consented for participation in the research study which includes a directed breast PET/MRI with 18F-FES. 18F-FES uptake of …

magnetic resonance imaging of breast
ductal carcinoma in situ
estrogen
  • 4 views
  • 18 Feb, 2022
  • 1 location
Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer

This phase 1b trial studies the biologic effect of 9cUAB30 on early stage breast cancer. 9cUAB30 is a retinoid X receptor (RXR)-selective retinoid that acts in a tissue selective manner with the goal of minimizing side effects, a necessary feature of agents under development for cancer prevention.

invasive breast cancer
breast cancer
therapeutic conventional surgery
fasting
cancer prevention
  • 31 views
  • 13 May, 2022
  • 3 locations
Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer

This phase II trial studies how well abemaciclib works in treating patients with triple negative breast cancer that can be removed by surgery (resectable) and does not respond to treatment with chemotherapy. Abemaciclib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

therapeutic conventional surgery
triple negative breast cancer
carboplatin
doxorubicin
metastases
  • 11 views
  • 24 Feb, 2022
  • 3 locations
An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors

This clinical trial evaluates the use of an Episodic Future thinking Intervention to promote weight loss in breast cancer survivors. Obesity is associated with multiple negative health sequelae in breast cancer survivors. This includes an increased risk of cancer recurrence and mortality, multiple quality of life issues, and increased risk …

breast surgery
carcinoma in situ
body mass index
cancer
breast cancer
  • 0 views
  • 22 Dec, 2021
  • 1 location
SABR-CaRe in Early Stage Breast Cancer

This phase II trial studies the effect of calorie reduction while undergoing stereotactic ablative radiation therapy in treating patients with breast cancer. Stereotactic ablative radiation therapy (sABR) is a highly focused radiation treatment that gives an intense dose of radiation concentrated on a tumor, while limiting the dose to the …

sentinel lymph node biopsy
body mass index
cancer
invasive breast cancer
breast cancer
  • 0 views
  • 06 May, 2022
  • 1 location