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Found 14 clinical trials
Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

Although the results obtained from ECOG E5194 cohort 1 (criteria: mammographically detected low- or intermediate-grade DCIS, measuring less than 2.5 cm with margins 3 mm) and RTOG 9804 trial (the same enrolled clinicopathological features to cohort 1 of ECOG E5194 trial) demonstrated that the 7-year ipsilateral breast tumor recurrence (IBTR) …

breast tumor
cancer
breast cancer
breast-conserving surgery
mammogram
  • 18 views
  • 14 Feb, 2022
  • 1 location
Effect of PACK Health Support Program on Patient Reported Outcomes in Patients With Breast Cancer

This trial studies the effect of an electronic health (eHealth) support program called PACK Health on patient reported health outcomes in patients with breast cancer. PACK Health monitors breast cancer patients' reported side effects and experience of care when receiving chemotherapy. Participating in the PACK Health coaching program may improve …

invasive breast cancer
carcinoma
carcinoma in situ
cancer
ductal carcinoma in situ
  • 4 views
  • 12 Jul, 2022
  • 1 location
Approaches to Identify and Care for Individuals With Inherited Cancer Syndromes

This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and …

genetic testing
cancer
Accepts healthy volunteers
breast cancer
BRCA2
  • 21 views
  • 14 Oct, 2022
  • 2 locations
Subzero and Scorpion Trial

This is a prospective single-institution pilot study examining the feasibility of performing ultrasound-guided cryoablation to completely ablate breast ductal carcinoma in situ (DCIS). The study

core needle biopsy
mammogram
carcinoma in situ
cancer
lobular carcinoma
  • 0 views
  • 11 Sep, 2021
  • 2 locations
Comparing Supplemental Topical Agents for the Treatment of Acute Radiation Dermatitis in Patients With Breast Cancer

This clinical trial compares two supplemental topical agents (Aquaphor and Miaderm) for the treatment of acute radiation dermatitis in patients with breast cancer undergoing radiation therapy. Radiation dermatitis is a radiation-induced skin reaction which can cause itching, swelling, pain, and general discomfort. Aquaphor is a commonly available, inexpensive, petrolatum-based multi-purpose …

invasive breast cancer
lumpectomy
mastectomy
carcinoma in situ
cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

This phase Ib trial studies the side effects and best dose of a vaccine called H2NVAC before surgery in treating patients with HER2 expressing ductal carcinoma in situ. H2NVAC is a vaccine designed to stimulate specialized white blood cells in hopes of increasing immune response and protecting against breast cancer.

immunohistochemistry
therapeutic conventional surgery
carcinoma in situ
erbb2
platelet count
  • 6 views
  • 16 Feb, 2022
  • 2 locations
Partial Chest Wall Radiation Therapy After Surgery for Lymph Node Negative Breast Cancer

The standard treatment for breast cancer when cancer cells were found near or within the margins of the tissue that is removed during breast surgery, is radiation of the entire chest wall. This may be considered overtreatment since the only reason for doing so is that cancer cells were near …

invasive breast cancer
mastectomy
breast surgery
cancer
breast cancer
  • 0 views
  • 07 Oct, 2022
  • 1 location
Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS

This prospective, one-arm study which will enroll participants with biopsy-proven DCIS scheduled for diagnostic breast MRI for preoperative staging/extent of disease evaluation as part of standard of care. Eligible participants will be consented for participation in the research study which includes a directed breast PET/MRI with 18F-FES. 18F-FES uptake of …

ductal carcinoma in situ
magnetic resonance imaging of breast
estrogen
  • 4 views
  • 04 Oct, 2022
  • 1 location
SABR-CaRe in Early Stage Breast Cancer

This phase II trial studies the effect of calorie reduction while undergoing stereotactic ablative radiation therapy in treating patients with breast cancer. Stereotactic ablative radiation therapy (sABR) is a highly focused radiation treatment that gives an intense dose of radiation concentrated on a tumor, while limiting the dose to the …

invasive breast cancer
breast cancer staging
cancer
breast cancer
sentinel lymph node biopsy
  • 0 views
  • 06 May, 2022
  • 1 location
An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors

This clinical trial evaluates the use of an Episodic Future thinking Intervention to promote weight loss in breast cancer survivors. Obesity is associated with multiple negative health sequelae in breast cancer survivors. This includes an increased risk of cancer recurrence and mortality, multiple quality of life issues, and increased risk …

carcinoma in situ
erbb2
HER2
breast surgery
cancer
  • 0 views
  • 22 Dec, 2021
  • 1 location