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Found 21 clinical trials
featured
EMERALD – Breast Cancer

People with breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.  

cancer
  • 54 views
  • 23 Nov, 2020
  • 1 location
featured
HER2 Negative Advanced Breast Cancer

People with HER2 negative advanced breast cancer are asked to participate in a research study being conducted by Queens Hospital Center.  

cancer
HER2
advanced breast cancer
  • 27 views
  • 28 Oct, 2019
  • 1 location
Study of Palbociclib and Trastuzumab With Endocrine Therapy in HER2-positive Metastatic Breast Cancer

PATRICIA is a phase II, open-label, multicentre, Simon's two-stage-design study of the combination of palbociclib plus trastuzumab, with or without letrozole, in post-menopausal patients with HER2-positive locally advanced or metastatic breast cancer (MBC) who have received chemotherapy and treatment with trastuzumab for their metastatic disease. Cohorts A, B1, and B2 …

endocrine therapy
HER2
liver metastasis
adenocarcinoma
neutrophil count
  • 15 views
  • 03 Aug, 2020
  • 23 locations
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic). Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor …

estrogen
placebo administration
HER2
measurable disease
estrogen receptor
  • 438 views
  • 17 Jan, 2021
  • 416 locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

estrogen
epidermal growth factor receptor
ductal carcinoma
absolute neutrophil count
sentinel node
  • 814 views
  • 05 Aug, 2019
  • 811 locations
Hypofractionated Regional Nodal Irradiation Clinical Trial for Women With Breast Cancer

Single-arm, phase 2 study evaluating hypofractionated irradiation of breast and regional nodes in women with breast cancer. Patients will be grouped in 3 surgery-related treatment groups: 1) An intact breast following lumpectomy; 2) plans for loco regional external beam radiotherapy (EBRT) following mastectomy (with or without plans for reconstruction); and …

core needle biopsy
estrogen
estrogen receptor
ductal carcinoma
sentinel node
  • 18 views
  • 22 Jul, 2020
  • 2 locations
Trial of H3B-6545 in Women With Locally Advanced or Metastatic Estrogen Receptor-positive HER2 Negative Breast Cancer

The purpose of phase 1 is to determine safety, tolerability and pharmacokinetics (PK) of H3B-6545 in women with locally advanced or metastatic estrogen receptor (ER)-positive, human epidermal growth factor 2 (HER2)-negative breast cancer. The purpose of phase 2 is to estimate the efficacy of H3B-6545 in terms of best overall …

estrogen
estrogen receptor
cancer
HER2
her2/neu-negative breast cancer
  • 114 views
  • 16 Sep, 2020
  • 20 locations
A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast Cancer

This phase I trial investigates the side effects and best dose of using a modified measles virus, MV-s-NAP, in treating patients with invasive breast cancer that has spread to other places in the body (metastatic). Both the unmodified vaccination measles virus (MV-Edm) and this modified virus (MV-s-NAP) have been shown …

endocrine therapy
measurable disease
epidermal growth factor receptor
neutrophil count
progesterone
  • 0 views
  • 01 Oct, 2020
Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones

This phase II trial studies how well radium-223 dichloride and paclitaxel work in treating patients with advanced breast cancer that has spread to the bones. Radium-223 dichloride is a radioactive drug that behaves in a similar way to calcium and collects in cancer that has spread to the bones (bone …

  • 0 views
  • 17 Jan, 2021
  • 8 locations
Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast Cancer

This phase II trial studies how well nab-paclitaxel and atezolizumab before surgery work in treating patients with triple negative breast cancer (breast cancer cells that do not have estrogen receptors, progesterone receptors, or large amounts of human epidermal growth factor receptor 2 protein). Drugs used in chemotherapy, such as nab-paclitaxel, …

estrogen
epidermal growth factor receptor
ductal carcinoma
HER2
neutrophil count
  • 0 views
  • 18 Jan, 2021
  • 1 location