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Found 1 clinical trials
Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD

This phase Ib/II trial studies the side effects of PLX51107 in treating steroid-refractory acute graft versus host disease (GVHD). PLX51107 is a novel, potent non-benzodiazepine structured small molecule BET inhibitor with a unique binding mode selective for BRD4 inhibition and a more tolerable side effect profile. PLX51107 may work better …

  • 23 Apr, 2022
  • 1 location