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Found 173 clinical trials
Retinal, Cerebral and Vascular Precursor Markers of Cerebral Small Vessel Disease. (SHIVA-SHARE)

blood pressure and arterial stiffness, in a young adult population. The main objective is to explore the association between these parameters and structural changes on brain MRI. Results will allow to

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 1 location
ADRC Clinical Cohort

3 study visits that will collect medical and family history surveys, a complete physical exam, blood tests and comprehensive memory/cognitive testing; also a Brain MRI imaging and a Lumbar

alzheimer's disease
Accepts healthy volunteers
  • 0 views
  • 26 Jan, 2022
  • 1 location
The Role of Icotinib in the Perioperative Treatment of IIIA - IIIB NSCLC Patients With EGFR Mutation

surgery should receive radiation therapy. Patients after surgery will receive long-term follow-up -- chest CT scanabdominal abdominal ultrasound every 3 months, brain MRI every 6 months, bone scan (ECT

lung carcinoma
EGFR
neutrophil count
kidney function test
platelet count
  • 16 views
  • 23 Feb, 2022
  • 1 location
Detection and Metabolic Characterization in DOPA PET/CT of Brain Metastases (DOPACER)

of these patients is unfavorable but prolonged survival can be obtained with the local and systemic treatments currently available. Brain MRI is the gold standard for evaluating brain

  • 0 views
  • 23 Mar, 2022
  • 2 locations
A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases

asymptomatic brain metastases will be treated with Osimertinib for 2 months. Brain MRI scans will be collected pre-Osimertinib and 2 months after treatment start. Patients with asymptomatic brain metastases

follicle stimulating hormone
osimertinib
brain metastases
EGFR
  • 0 views
  • 12 Sep, 2021
  • 1 location
Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery

enrolled subjects will undergo advanced brain MRI and neurocognitive evaluation to achieve these goals. The findings of this project will not guide any clinical decision-making or clinical intervention

seizure
epilepsy surgery
Accepts healthy volunteers
  • 0 views
  • 06 May, 2022
  • 1 location
A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression

perfusion or PET/CT that are within 12 weeks of each other. After one of these scans, the patient will have no active interventions and will be off study. Patients will obtain a standard of care brain MRI

cancer
meningioma
tumor progression
metastasis
malignant glioma
  • 8 views
  • 15 Jun, 2022
  • 6 locations
The Influence of Vascular Burden, Amyloid Plaque and Tau Protein in Patients With Vascular Cognitive Impairment and Dementia With Tauopathy

, brain MRI for obtaining structural and functional information, and neuropsychological tests for cognitive performance. Cognitive evaluation will be repeated 18 months after recruitment. In addition

Accepts healthy volunteers
  • 0 views
  • 02 Mar, 2022
  • 1 location
Modulation of Sense of Agency With Non-invasive Brain Stimulation and Mindfulness-based Stress Reduction Therapy

). The planned study methods include TMS, (real-time and normal) magnetic resonance tomography of the brain (MRI "tube"), virtual- and augmented reality (AR/VR), questionnaires, blood, saliva, and motion

Accepts healthy volunteers
  • 0 views
  • 11 Mar, 2022
  • 1 location
Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation

computer. Relaxing at the center until breath alcohol falls below 0.02 percent, or for 3 hours. Visits 2 and 3: Swallowing nalmefene or placebo. One-hour brain MRI

Accepts healthy volunteers
  • 9 views
  • 27 Jun, 2022
  • 1 location