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Found 228 clinical trials
Microglial Activation Positron Emission Tomography (PET) Brain Imaging in Multiple Sclerosis and Alzheimer's Disease

The specific aims of the study are: Primary: To determine the presence and regional distribution of microglial activation, as assessed by Fluorine-18 (18F) labeled "Peripheral Benzodiazepine Receptor 06" (PBR06) -PET, in subjects with active Relapsing Remitting Multiple Sclerosis (RRMS), Secondary Progressive Multiple Sclerosis (SPMS), and Alzheimer's Disease (AD) as compared …

relapsing multiple sclerosis
chronic progressive multiple sclerosis
atrophy
positron emission tomography
fatigue
  • 14 views
  • 26 Jan, 2021
  • 1 location
Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

Background Non-invasive functional near infrared (fNIR) imaging techniques use infrared light to detect changes in blood volume and oxygen levels during brain activity. fNIR is being studied as a possible way to examine the brain activity of individuals who are unable to undergo standard brain function imaging techniques (such as …

  • 0 views
  • 09 Jul, 2021
  • 1 location
Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

brain imaging with MRI or CT will also be enrolled and the diagnostic performance of low field scans compared to that of the same day standard of care clinical imaging.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Using Online Delivered Therapy and Brain Imaging to Better Understand OCD

This study will implement an e-CBT program for OCD and observe its effects on brain activation levels using functional magnetic resonance imaging (fMRI). It is hypothesized that brain activation levels in the basal ganglia and frontal cortex will decrease following treatment. Individuals with OCD will be offered a 16-week e-CBT …

  • 0 views
  • 25 Apr, 2021
  • 1 location
Longitudinal Validation of Neurofeedback in Stroke Motor Rehabilitation Through Brain Imaging

, allied to the use of rising of information and communication technologies (ICT). By identifying correlations on the neural activity, during motor imagery and through brain imaging (fMRI), with distinct

hemiplegia
brain imaging
hemiparesis
  • 0 views
  • 24 Jan, 2021
  • 1 location
A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol

receives MI with no stimulation. Measures will include brain imaging, alcohol use, cannabis use, risk-taking behavior, emotions, and others. Participants who are randomized to the delayed-treatment group

  • 0 views
  • 14 Mar, 2021
  • 1 location
Treating Primary Progressive Aphasia (PPA) Using tDCS

) will undergo language testing and structural and functional brain imaging before and after receiving 10 semi-consecutive daily sessions of real or sham transcranial direct current stimulation (tDCS

  • 0 views
  • 29 Apr, 2021
  • 1 location
Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS

) will undergo language testing and structural and functional brain imaging before and after receiving 10 semi-consecutive daily sessions of real or sham high-definition transcranial direct current

  • 0 views
  • 24 Jan, 2021
  • 1 location
A High Frequency Spinal Cord Stimulation PET-CT Scan Study

This study aims to investigate the clinical response to Spinal Cord Stimulation frequency parameters: 40Hz, 4000Hz and 10000Hz and explore the brain imaging changes using PET-CT scans. The

spinal cord
  • 0 views
  • 23 Jan, 2021
  • 1 location
Natural History Characterization in Symptomatic and Asymptomatic Progranuline Gene Mutation Carriers

. The main objectives of the project are to identify novel cognitive, brain imaging markers and peripheral biomarkers for early diagnosis of FTLD, and to follow disease progression.

dementia, frontotemporal
  • 0 views
  • 24 Jan, 2021
  • 3 locations