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Found 168 clinical trials
Featured trial
A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

  • 258 views
  • 08 Dec, 2020
  • 1 location
Featured trial
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 87 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Impact of sleep apnea and its treatment on memory and tau accumulation in the brain

The purpose of the research study is to address whether obstructive sleep apnea (OSA) represents a risk factor contributing to the development of Alzheimer’s disease (AD) that can be slowed by treatment with Positive Airway Pressure (PAP). Our preliminary data shows conversion to Mild Cognitive Impairment in self-reported PAP users …

mini-mental state examination
amyloid
mild cognitive impairment
cognitive impairment
  • 0 views
  • 25 Mar, 2022
  • 1 location
Featured trial
Role of Slow Waves and Sleep Apnea in Memory and Risk for Alzheimer's Disease

Untreated sleep apnea (short episodes of stopping breathing) is thought to contribute to difficulty with memory. The purpose of this study is determining what effects sleep apnea has on the specific ability to remember locations and as well as on proteins in your body that contribute to risk for Alzheimer …

  • 4 views
  • 25 Mar, 2022
  • 1 location
A Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (FENopta)

This is a study evaluating the effect of fenebrutinib on brain MRI in participants with RMS. The safety and pharmacokinetics of fenebrutinib will also be evaluated. Participants will be

  • 0 views
  • 27 Oct, 2022
  • 15 locations
Exploring the Relationship Between Advanced Multimodal Brain MRI Phenotypes, Genes and Cognitive Outcome in Adults With CHD

The main purpose of this proposal is to perform novel MRI analyses to determine the brain organizational changes associated with altered executive function and the modulating role of variants in neuroresilience and hypoxia response genes in adults with d-transposition of the great arteries (d-TGA).

Accepts healthy volunteers
  • 0 views
  • 16 Oct, 2022
  • 1 location
Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence

This is a randomized double-blind crossover trial of trospium and placebo in women with urgency urinary incontinence, with evaluation (history, physical, incontinence evaluation and brain MRI

  • 1 views
  • 04 Oct, 2022
  • 1 location
Effects and Mechanisms of Ocrevus on Ambulatory Functions in People With Relapsing Multiple Sclerosis (MOBILE-RMS)

regulations over the one-year course. Their ambulatory functions will be assessed five times three months apart. In addition, they will receive brain MRI scans three times six months apart. Their ambulatory

  • 0 views
  • 15 Oct, 2022
  • 2 locations
Longitudinal Neuroimaging in Sturge-Weber Syndrome

affected patients. All enrolled subjects will undergo advanced brain MRI and neurocognitive evaluation to achieve these goals.

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Phase II Trial of Non-Invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders

have a baseline visit. This will include: Neurological exam Questionnaires Urine test Brain MRI: Participants will lie in a machine that takes pictures of the body. They

  • 0 views
  • 21 Oct, 2022
  • 1 location