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Found 169 clinical trials
Featured trial
A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

  • 258 views
  • 08 Dec, 2020
  • 1 location
Featured trial
Impact of sleep apnea and its treatment on memory and tau accumulation in the brain

The purpose of the research study is to address whether obstructive sleep apnea (OSA) represents a risk factor contributing to the development of Alzheimer’s disease (AD) that can be slowed by treatment with Positive Airway Pressure (PAP). Our preliminary data shows conversion to Mild Cognitive Impairment in self-reported PAP users …

cognitive impairment
mild cognitive impairment
amyloid
mini-mental state examination
  • 0 views
  • 25 Mar, 2022
  • 1 location
Featured trial
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 87 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Role of Slow Waves and Sleep Apnea in Memory and Risk for Alzheimer's Disease

Untreated sleep apnea (short episodes of stopping breathing) is thought to contribute to difficulty with memory. The purpose of this study is determining what effects sleep apnea has on the specific ability to remember locations and as well as on proteins in your body that contribute to risk for Alzheimer …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Cohort of Healthy People in Brain MRI, Together With a Language and Cognitive Assessment at the University Hospital of Nice (NHB)

The aim of this study is to constitute a cohort of healthy subjects in brain MRI, including functional and diffusion sequences, together with a language and cognitive assessment. This will make

Accepts healthy volunteers
  • 0 views
  • 23 Apr, 2022
  • 1 location
A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS) (FENopta)

This is a study evaluating the effect of fenebrutinib on brain MRI in participants with RMS. The safety and pharmacokinetics of fenebrutinib will also be evaluated. Participants will be

  • 0 views
  • 26 Apr, 2022
  • 3 locations
Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence

This is a randomized double-blind crossover trial of trospium and placebo in women with urgency urinary incontinence, with evaluation (history, physical, incontinence evaluation and brain MRI

  • 1 views
  • 28 Feb, 2022
  • 1 location
Effects of Ocrevus in Relapsing Multiple Sclerosis

course. Their ambulatory functions will be assessed five times three months apart. In addition, they will receive brain MRI scans three times six months apart. Their ambulatory functions and MRI

  • 0 views
  • 28 Sep, 2021
  • 2 locations
OMEGA, Local Ablative Therapy in Oligometastatic NSCLC (OMEGA)

tumors has been designed. Inclusion criteria include adequate performance status, primary tumor controlled or controllable staging with whole-body FDG PET scan and brain MRI, fit to receive at

ct scan
stage iv non-small cell lung cancer
metastasis
brain metastases
platinum doublet
  • 0 views
  • 24 Feb, 2022
  • 1 location
Longitudinal Neuroimaging in Sturge-Weber Syndrome

affected patients. All enrolled subjects will undergo advanced brain MRI and neurocognitive evaluation to achieve these goals.

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location