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Found 142 clinical trials
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A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

  • 142 views
  • 08 Dec, 2020
  • 1 location
featured
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 82 views
  • 25 Mar, 2021
  • 1 location
Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients

with brain MRI every 3 months and rechallenging with TMZ at relapse (Stop and Go arm).

cancer
karnofsky performance status
temozolomide
methionine
  • 65 views
  • 07 Nov, 2020
  • 1 location
Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence

This is a randomized double-blind crossover trial of trospium and placebo in women with urgency urinary incontinence, with evaluation (history, physical, incontinence evaluation and brain MRI

  • 1 views
  • 10 Jun, 2021
  • 1 location
[18F]Fluciclovine in Post-treatment Glioblastoma ( Axumin )

suspected progression before planned surgery. In addition, clinical brain MRI with and without contrast will be used to evaluate the tumor pre-operatively. This is a non-therapeutic trial in that imaging

karnofsky performance status
chemoradiotherapy
  • 1 views
  • 25 Jul, 2021
  • 1 location
Effects of Ocrevus in Relapsing Multiple Sclerosis

course. Their ambulatory functions will be assessed five times three months apart. In addition, they will receive brain MRI scans three times six months apart. Their ambulatory functions and MRI

  • 0 views
  • 11 May, 2021
  • 2 locations
OMEGA Local Ablative Therapy in Oligometastatic NSCLC

tumors has been designed. Inclusion criteria include adequate performance status, primary tumor controlled or controllable staging with whole-body FDG PET scan and brain MRI, fit to receive at

carboplatin
lung carcinoma
cancer chemotherapy
EGFR
metastasis
  • 0 views
  • 23 Jan, 2021
  • 1 location
Longitudinal Neuroimaging in Sturge-Weber Syndrome

affected patients. All enrolled subjects will undergo advanced brain MRI and neurocognitive evaluation to achieve these goals.

  • 0 views
  • 25 Jan, 2021
  • 1 location
High-dose Vitamin D Supplements in Older Adults

brain MRI scans will be enrolled, with 152 (~50 with MCI, 50 with mild AD and 50 with no cognitive impairment) expected to complete the 3-year study. One-half of each diagnostic group will be randomized

  • 0 views
  • 23 Nov, 2020
  • 1 location
Prognostic Value of Arterial Spin Labeling Brain Perfusion MRI in Term Neonates With Hypoxic-ischemic Encephalopathy

The main purpose of this study will be to evaluate the prognostic value at 3 months of life of brain perfusion MRI determined by Arterial Spin Labeling technique in the first week of life of term newborns with hypoxic-ischemic encephalopathy requiring management in neonatal intensive care unit.

  • 0 views
  • 25 Jan, 2021
  • 1 location