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Found 141 clinical trials
Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer

Hypo-Combi Trial: A Prospective Phase I/II Study of Combined Hypofractionated External Beam Radiation Therapy (EBRT) plus Interstitial High-Dose-Rate Brachytherapy (HDR-BT) for Intermediate/High

  • 0 views
  • 23 Aug, 2021
  • 1 location
Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression

central androgen suppression and brachytherapy.

androgen suppression
brachytherapy
androgens
flutamide
  • 0 views
  • 06 Feb, 2022
  • 1 location
Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery

This is a prospective phase II study to assess the efficacy and toxicity of HSV-tk+ valacyclovir gene therapy in combination with androgen deprivation therapy, brachytherapy, external beam

adenocarcinoma of prostate
androgen suppression
brachytherapy
prostatectomy
bicalutamide
  • 3 views
  • 15 Feb, 2022
  • 1 location
Frontline Immunotherapy Combined With Radiation and Chemotherapy in High Risk Endometrial Cancer (FIERCE)

The purpose of this single arm, open label study is to evaluate the feasibility of pembrolizumab combined with radiation administered to the upper part of the vagina (vaginal cuff brachytherapy

lymphadenectomy
endometrial carcinoma
brachytherapy
carboplatin
hysterectomy
  • 0 views
  • 28 Feb, 2022
  • 1 location
A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer

The purpose of this study is to find out whether combining a shorter than standard course of ADT with standard prostate brachytherapy and hypofractionated external beam radiation therapy is a

  • 0 views
  • 25 Jul, 2022
  • 7 locations
Registry of Sarcoma Patients Treated With Permanently Implantable LDR CivaSheet®

This patient study will determine the safety and toxicity of a permanently implantable brachytherapy source - CivaSheet® - which is designed to deliver a therapeutic dose of low dose rate (LDR

  • 0 views
  • 13 Mar, 2022
  • 1 location
Salvage Cryotherapy for Recurrent Prostate Cancer After Radiation Therapy

prostate (SCAP). Our study hypothesis is that SCAP constitutes an effective and safe approach to treat local prostate cancer recurrence after brachytherapy or external beam radiation therapy (EBRT

  • 0 views
  • 25 May, 2021
  • 2 locations
Clinical Response and Toxicity of Hypo-fractionated Chemoradiotherapy in Cervix Cancer

Uterine cervix cancer can be treated definitively with concurrent chemoradiation (external beam radiotherapy and chemotherapy) followed by high dose rate brachytherapy. Treatment duration can be

Accepts healthy volunteers
  • 0 views
  • 21 Oct, 2021
  • 1 location
Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®

This is a feasibility study to determine the usefulness of a brachytherapy device that utilizes active components (palladium-103) of standard devices in a novel configuration, which may benefit

lung cancer
ct scan chest
ct scan
cancer
lung carcinoma
  • 1 views
  • 06 Jun, 2022
  • 2 locations
Optimizing Prostate Cancer Treatment in Men With Advanced Local Disease (OPTiMAL)

Multi-modality therapy that includes a brachytherapy implant improves outcomes in locally advanced prostate cancer when compared to other radiation-based treatments, but is also associated with

androgen suppression
brachytherapy
pet/ct scan
ct scan
transrectal ultrasound
  • 18 views
  • 12 Feb, 2022
  • 1 location