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Found 148 clinical trials
PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer (PORTEC-4a)

and molecular risk profile to determine if participants should receive no adjuvant therapy, vaginal brachytherapy or external beam radiotherapy based on a favourable, intermediate or unfavourable

  • 76 views
  • 01 Mar, 2022
  • 30 locations
PROfiling Based Endometrial Cancer Adjuvant Therapy (PROBEAT)

integrated genomic-pathologic classification to determine if participants should receive no adjuvant therapy, vaginal brachytherapy, external beam radiotherapy or chemo-radiation therapy based on molecular

  • 0 views
  • 10 May, 2022
  • 1 location
Image Guided IMRT, Radiochemotherapy and MRI-based IGABT in Locally Advanced Cervical Cancer (EMBRACEII)

- and brachytherapy. The aim of the EMBRACE II study is to maintain and enhance the excellent local tumor control as well as the nodal and systemic control for all tumor stages while minimizing the

cancer
squamous cell carcinoma
brachytherapy
cervical disease
pet/ct scan
  • 4 views
  • 12 Feb, 2022
  • 1 location
Pelvic RT Versus Prophylactic Extended-field RT in Patients With Cervical Cancer

To investigate the value of prophylactic extended-field irradiation (EFI), we conduct a randomized clinical trial to compare the efficacy and toxicity of pelvic irradiation and prophylactic EFI in selected patients with cervical cancer treated with definitive concurrent chemoradiotherapy. External beam radiation therapy is delivered with intensity-modulated radiation therapy (IMRT).

adenosquamous carcinoma
cancer
squamous cell carcinoma
metastasis
cervical neoplasm
  • 17 views
  • 12 Mar, 2022
  • 2 locations
Neoadjuvant Chemotherapy + Surgery Versus Surgery in FIGO IB2 and IIA2 Cervical Cancer (SYSGO-003)

To clarify the potential benefits of NACT before radical surgery(RS), we perform a phase III, randomised controlled trial to compare NACT plus RS with RS alone in patients with stages IB2 and IIA2 cervical cancer.

  • 13 views
  • 01 Mar, 2022
  • 1 location
Application of KANG FU PEN in Radical Concurrent Radiotherapy and Chemotherapy for Cervical Cancer to Prevent and Treat Radiation-induced Rectal Injury

A total of 520 cases will be randomly divided into Kang Fu Pen (liquid dressing) enema intervention group (experimental group) and non-enema intervention group (control group), according to the ratio of 1:1.

  • 0 views
  • 08 Apr, 2021
  • 1 location
An Efficacy Study of the Xoft® Axxent® eBx® IORT System® "Lite"

The purpose of this trial is to assess the efficacy of the Xoft Axxent eBx System when used for single-fraction IORT in early stage breast cancer. A comparison will be made to the current standard of care, whole breast irradiation (WBI), in women with early stage breast cancer.

carcinoma in situ
ductal carcinoma
intraoperative radiation therapy
cancer
ductal carcinoma in situ
  • 0 views
  • 13 Jun, 2022
  • 1 location
Tri-weekly Cisplatin Based Chemoradiation in Locally Advanced Cervical Cancer

Current standard treatment for locally advanced cervical cancer is cisplatin-based concurrent chemoradiation (CRT). Although recently reported meta-analysis studies also demonstrated improved local control rates and survival with cisplatin-based chemotherapy concurrent to radiation therapy (RT), the optimal cisplatin dose and dosing schedule are still undetermined. In light of the results of …

adenosquamous carcinoma
cancer
squamous cell carcinoma
chemoradiotherapy
carcinoma
  • 133 views
  • 22 Jan, 2021
  • 6 locations
RISI in the Treatment of Recurrent Metastatic SCC of Thoracic Inlet Lymph Nodes

The malignant tumor at the thoracic entrance is difficult to be surgically removed, and radiotherapy or radiotherapy based comprehensive treatment is often chosen at the initial diagnosis. However, for patients with recurrence after radiotherapy, there is basically no ideal local treatment.The Radioactive i-125 Seed Implantation (RISI) therapy is characterized by …

cancer
metastasis
metastatic squamous cell carcinoma
anticoagulants
diabetes
  • 0 views
  • 18 Jun, 2022
  • 1 location
A Novel Tapered Applicator for Vaginal Vault Brachytherapy

This study will assess the comfort and fit of a novel applicator for endometrial cancer patients who are candidates for vaginal brachytherapy. This study is only assessing the applicator fitting

cancer
brachytherapy
hysterectomy
  • 0 views
  • 12 Sep, 2021
  • 1 location