Found 165 clinical trials
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Oncology
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Currently Recruiting
Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients
The researchers plan: - To undertake clinical studies of radiotherapy with or without the administration of the chemotherapeutic agent cisplatin, known to be a radiosensitizer; - To perform pre-clinical studies of the radiosensitivity of human fibroblasts and cervical cancer cell lines in culture, with or without the addition of various …
- 197 views
- 07 Nov, 2020
- 3 locations
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For males only
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Currently Recruiting
PSMA-PET Registry for Recurrent Prostate Cancer
This study aims to institute a province-wide registry leveraging the availability of a new Positron Emission Tomography tracer, [18F]-DCFPyL and PET expertise across Ontario centers to improve our ability to characterize patterns of recurrence and personalize therapies in men with recurrent prostate cancer after primary treatment.
- 50 views
- 25 Jan, 2021
- 8 locations
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Currently Recruiting
High-Dose-Rate Brachytherapy
This pilot study initiates a research program testing the early technical and clinical performance of a novel procedure for MRI-guided high-dose-rate (HDR) prostate brachytherapy. Testing will
- 9 views
- 23 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For males only
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Currently Recruiting
Partial Prostate Salvage High Dose Rate Brachytherapy
% of patients treated because of inability to deliver sufficient dose through external beam techniques. These patients respond well to re-irradiation using brachytherapy with about 50% of selected
- 4 views
- 23 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours
The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected
- 0 views
- 22 Jan, 2021
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
AGuIX Gadolinium-based Nanoparticles in Combination With Chemoradiation and Brachytherapy
This is a phase 1 clinical trial evaluating the safety, tolerability of escalating doses of AGuIX-NP in combination with radiation and cisplatin in patients with locally advanced cervical cancer. Dose escalation will be conducted using the modified toxicity probability interval (mTPI) method. Three dose levels of intravenous AGuIX nanoparticles will …
- 11 views
- 22 Jan, 2021
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Oncology
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Currently Recruiting
Partial Breast Irradiation With Interstitial High Dose Rate Brachytherapy
demonstrated that most breast cancer recurrences after BCS occur close to the tumour bed. In our phase II prospective study PBI is administered with high-dose-rate brachytherapy in patients with low
- 0 views
- 07 Nov, 2020
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
Feasibility Study for Ultrasound-Guided Interstitial Brachytherapy for Gynecological CancersV2
Brachytherapy treatment in gynecological cancers is an essential component to delivering adequate doses of radiation to a tumour while sparing normal tissue. Interstitial and intracavitary
- 0 views
- 24 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For males only
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Currently Recruiting
HDR vs LDR Brachytherapy as Monotherapy in the Treatment of Localized Prostate Cancer.
Investigators compare in a randomized clinical trial the results and side effects of high-dose- and low-dose-rate brachytherapy as monotherapy in the treatment of early, organ confined
- 18 views
- 08 Nov, 2020
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For males only
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Currently Recruiting
Focal Salvage HDR Brachytherapy for Locally Recurrent Prostate Cancer in Patients Treated With Prior Radiotherapy
This purpose of this study is to evaluate the safety and effectiveness of a technique called focal high-dose-rate (HDR) brachytherapy as treatment for prostate cancer that has come back in the
- 8 views
- 24 Jan, 2021
- 2 locations