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Found 165 clinical trials
Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients

The researchers plan: - To undertake clinical studies of radiotherapy with or without the administration of the chemotherapeutic agent cisplatin, known to be a radiosensitizer; - To perform pre-clinical studies of the radiosensitivity of human fibroblasts and cervical cancer cell lines in culture, with or without the addition of various …

radiosensitizer
cervical carcinoma
chemotherapeutic agent
cancer
  • 197 views
  • 07 Nov, 2020
  • 3 locations
PSMA-PET Registry for Recurrent Prostate Cancer

This study aims to institute a province-wide registry leveraging the availability of a new Positron Emission Tomography tracer, [18F]-DCFPyL and PET expertise across Ontario centers to improve our ability to characterize patterns of recurrence and personalize therapies in men with recurrent prostate cancer after primary treatment.

prostatectomy
positron emission tomography
bone scan
karnofsky performance status
ct scan
  • 50 views
  • 25 Jan, 2021
  • 8 locations
High-Dose-Rate Brachytherapy

This pilot study initiates a research program testing the early technical and clinical performance of a novel procedure for MRI-guided high-dose-rate (HDR) prostate brachytherapy. Testing will

  • 9 views
  • 23 Jan, 2021
  • 1 location
Partial Prostate Salvage High Dose Rate Brachytherapy

% of patients treated because of inability to deliver sufficient dose through external beam techniques. These patients respond well to re-irradiation using brachytherapy with about 50% of selected

external beam radiation therapy
ct scan
antiandrogen therapy
brachytherapy
bone scan
  • 4 views
  • 23 Jan, 2021
  • 1 location
Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours

The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected

  • 0 views
  • 22 Jan, 2021
AGuIX Gadolinium-based Nanoparticles in Combination With Chemoradiation and Brachytherapy

This is a phase 1 clinical trial evaluating the safety, tolerability of escalating doses of AGuIX-NP in combination with radiation and cisplatin in patients with locally advanced cervical cancer. Dose escalation will be conducted using the modified toxicity probability interval (mTPI) method. Three dose levels of intravenous AGuIX nanoparticles will …

adenocarcinoma
coronary artery disease
external beam radiotherapy
cancer
aguix-np
  • 11 views
  • 22 Jan, 2021
Partial Breast Irradiation With Interstitial High Dose Rate Brachytherapy

demonstrated that most breast cancer recurrences after BCS occur close to the tumour bed. In our phase II prospective study PBI is administered with high-dose-rate brachytherapy in patients with low

breast cancer staging
partial breast irradiation
early-stage breast cancer
  • 0 views
  • 07 Nov, 2020
  • 1 location
Feasibility Study for Ultrasound-Guided Interstitial Brachytherapy for Gynecological CancersV2

Brachytherapy treatment in gynecological cancers is an essential component to delivering adequate doses of radiation to a tumour while sparing normal tissue. Interstitial and intracavitary

adenocarcinoma
cancer
  • 0 views
  • 24 Jan, 2021
  • 1 location
HDR vs LDR Brachytherapy as Monotherapy in the Treatment of Localized Prostate Cancer.

Investigators compare in a randomized clinical trial the results and side effects of high-dose- and low-dose-rate brachytherapy as monotherapy in the treatment of early, organ confined

brachytherapy
prostate specific antigen
cancer
  • 18 views
  • 08 Nov, 2020
  • 1 location
Focal Salvage HDR Brachytherapy for Locally Recurrent Prostate Cancer in Patients Treated With Prior Radiotherapy

This purpose of this study is to evaluate the safety and effectiveness of a technique called focal high-dose-rate (HDR) brachytherapy as treatment for prostate cancer that has come back in the

  • 8 views
  • 24 Jan, 2021
  • 2 locations