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Found 44 clinical trials
A Prospective Pilot Study to Assess the Efficacy of BOTOX-A in Patients With Low Anterior Resection Syndrome (LARS>20) and Refractory Medical Treatment After Rectal Resection

, and faecal incontinence. The goal of this study is to test intra-rectal BOTOX-A on functional outcomes and quality of life of patients with LARS refractory to medical treatment at 3 months after

  • 20 Oct, 2021
  • 1 location
Trigger Point Injections in Anterior Cervical Surgery

botox injections or dry needling, and equivalent to physical therapy. However, these studies were performed on patients with chronic neck pain. There are no studies evaluating the effectiveness of

  • 25 Apr, 2021
  • 1 location
Effects of Neuromodulation in Laryngeal Dystonia

and Botulinum Toxin (Botox) injections to the posterior cricoarytenoid (PCA) and/or TA (thyroarytenoid) often bilaterally, to alleviate muscle spasms in the vocal folds. However, the effects of

Accepts healthy volunteers
  • 06 Nov, 2021
  • 1 location
Assessment of the Neuro-glio-epithelial Unit (NGEU) in Biopsies Taken During Peroral Endoscopic Myotomy (POEM) for Achalasia: a Feasibility and Safety Study.

opportunity to better understand its underlying pathophysiological mechanisms. Currently available treatments for achalasia (pneumatic dilation (PD), Heller's myotomy (HM), botox injections, POEM) are

esophageal motility disorder
heller myotomy
peroral endoscopic myotomy
  • 13 Jan, 2022
  • 1 location
Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer

This randomized phase II trial studies how well botulinum toxin type A works in preventing complication after surgery in patients with esophageal cancer. Botulinum toxin type A may cause less complications of nausea and vomiting after surgery.

esophageal cancer
  • 29 Sep, 2021
  • 1 location
Spasmodic Dysphonia Pain

This study aims to identify adjuvant methods to improve patient comfort during in-office laryngology procedures.

  • 06 Oct, 2021
  • 1 location
Laryngeal Vibration for Spasmodic Dysphonia

The general aim of the research is to provide scientific evidence that VTS represents a non-invasive form of neuromodulation that can induce measurable improvements in the speech of SD patients. This research addresses a clinical need to develop alternative or auxiliary treatments for a rare voice disorder with limited treatment …

Accepts healthy volunteers
  • 07 Oct, 2021
  • 1 location
Posterior Tibial Nerve Stimulation (PTNS) Plus Mirabegron to Treat Refractory OAB Symptoms (PTNS-M Study)

Abstract Introduction: Urgency Urinary Incontinence (UUI) is a common condition with a prevalence of 9-31% in women in the United States. Despite current treatments, a high number of women have symptoms refractory to first- and second-line treatment approaches. Aims: The primary aim of this randomized controlled trial is to compare …

Accepts healthy volunteers
percutaneous tibial nerve stimulation
  • 15 Dec, 2021
  • 1 location
Trip-Tox Effectiveness of Triptans Before and After Onabotulinumtoxin A Treatment in Chronic Migraine

Observational, longitudinal, prospective, prospective, comparative study of the effectiveness of triptans before and after onabotulintoxin A initiation in a single group of chronic migraine patients.

  • 10 Oct, 2021
Obturator Cryoneurotomy for Hip Adductor Spasticity

The purpose of the study is to measure the effects of obturator nerve cryoneurotomy, on clinical measures in adult (ages 19+) and paediatric (ages 12-18) patients with hip adductor spasticity, who will receive this procedure as a part of their treatment based on the spasticity treatment available guidelines. The results …

  • 13 Dec, 2021
  • 1 location