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Found 272 clinical trials
Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

The objective of the proposed work is to determine whether administration for 12 months of romosozumab followed by 12 months of denosumab will maintain bone mass at the knee in subjects with

  • 0 views
  • 16 Jan, 2022
  • 2 locations
The Effectiveness in the Treatment of Long Bone Defect Using 3D-printed Implant

To evaluate the effectiveness of 3D-printed titanium alloy implants in the treatment of long bone defect in adults

  • 0 views
  • 16 Aug, 2021
  • 1 location
Melatonin and Osteogenic Loading on Osteopenia

This study will be assessing the efficacy of melatonin and/or osteogenic loading on modulating bone health in an osteopenic population.

melatonin
osteopenia
dual-energy x-ray absorptiometry
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery

Bariatric surgery leads to bone loss and increases fracture risk. This study evaluates whether denosumab can prevent the high-turnover bone loss that occurs after Roux-en-Y Gastric Bypass (RYGB) and sleeve gastrectomy (SG) surgery.

zoledronic acid
denosumab
gastric bypass
roux-en-y
gastrectomy
  • 1 views
  • 25 Jan, 2021
  • 1 location
The Effect of Semaglutide on Bone Turnover in Patients With Increased Risk of Bone Fracture

The hypothesis for this study is that the GLP-1Ra Semaglutide has a positive effect on the balance between build-up and degradation as well as the strength of the bones in men and women aged 40-85 years at increased risk of bone fractures. Treatment involves injection of Semaglutide 1.34 mg/ml once …

  • 0 views
  • 07 Apr, 2021
  • 1 location
"Surgical vs. Non-surgical Peri-implant Therapy"

The aim of this randomized clinical trial is to evaluate the effectiveness, in terms of clinical and radiographic changes, of non-surgical peri-implant therapy (mechanical/chemical) versus regenerative surgical therapy (xenograft and collagen membrane), after a follow-up period of 12 months.

Accepts healthy volunteers
debridement
  • 0 views
  • 03 Jan, 2022
  • 1 location
Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor

This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor called Recombinant Human Platelet-Derived Growth Factor (rhPDGF).

  • 22 views
  • 09 Sep, 2021
  • 1 location
Healthy Body Healthy Bones After Bariatric Surgery Trial

One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with bariatric surgery adversely affects bone leads to an increased risk of fracture. Bisphosphonate medications, such as zoledronic acid, …

zoledronic acid
osteoporosis
Accepts healthy volunteers
bisphosphonate
  • 0 views
  • 19 Nov, 2021
  • 1 location
Examination How the Administration Period of Teriparatide Affects Bone Metabolism and Bone Mineral Density Prior to Denosumab Therapy

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in osteoporosis patients: The administration period of teriparatide is less than 6 months and thereafter, denosumab for 24 months. The administration period of teriparatide is from 6 to 12 months and thereafter, …

denosumab therapy
denosumab
bone mineral density
forteo
teriparatide
  • 130 views
  • 29 Sep, 2021
  • 1 location
Changes of Bone Metabolic Markers and Bone Mineral Density After Denosumab and/or Teriparatide Treatment in Japanese Osteoporotic Patients

It has not been well known about the changes of bone metabolic markers, bone mineral density and other bone-related markers after teriparatide and/or denosumab treatment in Japanese osteoporotic

denosumab
teriparatide
bone mineral density
  • 39 views
  • 25 Jan, 2021
  • 1 location