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Found 21 clinical trials
A Randomized Multicenter Pragmatic Trial Comparing Bone Pain From a Single Dose of Pegfilgrastim to 5 Doses of Daily Filgrastim in Breast Cancer Patients Receiving Neoadjuvant/Adjuvant Chemotherapy

REaCT-5G will compare bone pain from a single dose of Pegfilgrastim to 5 doses of daily filgrastim in breast cancer patients receiving neoadjuvant/adjuvant chemotherapy.

  • 26 Jun, 2021
  • 1 location
Improving White Blood Cell Collection From Healthy Donors

Background White blood cells called granulocytes help the body fight infection. People who have had chemotherapy or bone marrow transplants may have very low numbers of these cells. Transfusions of these cells can help improve the body's ability to fight infection. However, most of the cells are located in the …

Accepts healthy volunteers
  • 20 Jun, 2022
  • 1 location
Dietary and Exercise Interventions in Reducing Side Effects in Patients With Stage I-IIIa Breast Cancer Receiving Aromatase Inhibitors

Mediterranean dietary and bone strengthening exercise interventions may alleviate medication side effects such as joint and bone pain and protectively influence bone mineral density, improve heart functioning

aromatase inhibition therapy
aromatase inhibitor
breast carcinoma
bone pain
  • 05 Jun, 2022
  • 1 location
Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

This phase II trial studies how well low-dose radiotherapy works in treating bone pain in patients with multiple myeloma that has spread to the bone. Radiation therapy uses high energy x-rays

chemotherapy regimen
bone pain
tumor cells
  • 11 Mar, 2022
  • 7 locations
ERAS Anesthetic Care for Metastatic Spine Cancer Resection

bloc spondylectomy with wide margin of resection facilitate the improvement in quality of life including ambulatory ability, daily activities independence and attenuation of bone pain. However, En bloc

  • 28 Jun, 2022
  • 1 location
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases (FURTHER)

The FURTHER study aims to evaluate the effectiveness and cost-effectiveness of MR-HIFU (alone or in combination with EBRT) compared to EBRT alone, the standard-of-care, as a palliative treatment option to relieve CIBP. This multicenter, three-armed randomized controlled trial will be performed in six hospitals in four European countries, and will …

palliative care
bone metastases
bone lesion
  • 01 Mar, 2022
  • 2 locations
Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients

pain is worse than the cancer. The golden standard to manage pain is opioids. Patients with cancer-induced bone pain are now taking increasing doses of opioids to control their pain. Sadly, opioids

  • 21 Mar, 2022
  • 2 locations
Sensitivity, Threshold, Tolerance and Pain Recognition in Schizophrenia Patients and Their Relatives.

analgesic effect of quetiapine in the Cancer-induced bone pain animal model have been demonstrated. However, the mechanism of action to relive pain is still under debate and may differ between different

psychiatric symptoms
Accepts healthy volunteers
  • 12 May, 2022
  • 1 location
Treatment and Natural History Study of Lymphomatoid Granulomatosis

interferon. Alpha interferon can have flu-like side effects of headache, fever, chills, and body aches. EPOCH-R drugs can cause gastrointestinal problems, hair loss, and weakness. G-CSF can cause bone pain

cancer chemotherapy
bone marrow procedure
b-cell lymphoma
  • 19 Jun, 2022
  • 1 location
Chemotherapy Supported by Autologous Hematopoietic Stem Cells

The aim of this project is to use autologous haematopoietic stem cell transfusion support to promote the reconstruction of haematopoietic function after chemotherapy for ovarian cancer. To explore the impact of stored haematopoietic stem cell support therapy on bone marrow protection after conventional chemotherapy for ovarian cancer in order to …

cancer chemotherapy
cancer of the ovary
  • 17 Jun, 2022
  • 1 location