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Found 62 clinical trials
featured
Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma(CLL/SLL), Lymphoplasmacytic Lymphoma(LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma(SMZL)

drawn. When required patients may undergo additional testing that may include bone marrow biopsy and aspiration, blood drawing, lymph node biopsy, x-ray studies, positron emission tomography and CT and

lymphocytosis
lymphoma
cancer
chronic lymphocytic leukemia
marginal zone lymphoma
  • 88 views
  • 15 Apr, 2019
  • 1 location
featured
A Randomized Trial of Sirolimus (Rapamune) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

screened with: Medical history Physical exam Blood and urine tests Bone marrow biopsy: The area above the hipbone will be numbed. A thin needle will remove&nbsp

myelodysplastic syndromes
aplastic anemia
anemia
anemia studies
myelodysplastic syndrome (mds)
  • 61 views
  • 22 Dec, 2020
  • 1 location
featured
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

> Bone marrow biopsy CT scan Recipients will have an IV line placed into a vein in the neck. Starting 11 days before the transplant they will have several chemotherapy

myelodysplastic syndrome (mds)
aplastic anemia
anemia studies
myelodysplastic syndromes
  • 57 views
  • 22 Dec, 2020
  • 1 location
featured
A Study of the Kinetics of Lymphoid Cells in Patients with Monoclonal B-Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL) and Healthy Volunteers

additional heavy water will be consumed. Blood samples will be collected weekly during the labeling period, and a bone marrow biopsy will be obtained where possible. Individuals with cancer may also

mantle cell lymphoma
lymphocytosis
lymphoma
chronic lymphocytic leukemia
cancer
  • 102 views
  • 15 Apr, 2019
  • 1 location
featured
Low-Dose Danazol for the Treatment of Telomere Related Diseases

DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes can develop diseases of the bone marrow, lung, and liver. Researchers want to see …

lung disease
anemia
pulmonary fibrosis
liver disease
hepatic fibrosis
  • 293 views
  • 22 Dec, 2020
  • 1 location
Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Physical exam Blood and urine tests Bone marrow biopsy: The area above the hipbone will be numbed. A thin needle will remove some bone marrow. Participants will

immunosuppression
aplastic anemia
blood test
sirolimus
platelet count
  • 7 views
  • 02 Apr, 2021
  • 1 location
Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)

> Participants will be screened with: medical history physical exam electrocardiogram blood tests family history bone marrow biopsy current

immunosuppression
blood disorder
aplastic anemia
blood test
platelet count
  • 1 views
  • 27 Feb, 2021
  • 1 location
Encorafenib Plus Binimetinib for People With BRAF V600E Mutated Relapsed/Refractory HCL

Bone marrow biopsy: A needle will be injected through the participant s skin and into a bone to remove liquid. Blood and urine tests Heart and lung function tests CT or

  • 0 views
  • 20 Mar, 2021
  • 1 location
Detection of Recurrent Mutations in Waldenstr m's Disease

are based on protein electrophoresis from a blood sample to quantify monoclonal IgM production and a myelogram or bone marrow biopsy showing medullary infiltration by lymphoplasmocytic cells. However

  • 0 views
  • 24 Jan, 2021
  • 1 location
Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

with: Medical history Physical exam Blood and urine tests Lung and heart tests Eye exam Bone marrow biopsy: A needle will be injected

  • 0 views
  • 22 Mar, 2021
  • 1 location