Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 11 clinical trials
Therascreen® KRAS RGQ PCR Kit

An interventional, prospective IVD device study for the testing of DNA extracted from tumor tissue biopsy samples from patients with Colorectal Cancer (CRC) who have previously tested positive for the KRAS G12C mutation for potential inclusion into the Amgen Phase III clinical trial (Protocol No 20190172) to demonstrate clinical performance …

  • 0 views
  • 14 May, 2022
  • 1 location
Novel Combination Therapy for Osteoporosis in Men (Osteo-Men)

Osteoporotic fractures are a key health problem in older men. Although there are drugs approved to treat osteoporosis in men [bisphosphonates, denosumab, and teriparatide (TPTD) or PTH(1-34)], there is a lack of knowledge on how to use them effectively. TPTD is a potent bone anabolic drug, meaning that it builds …

  • 34 views
  • 26 Feb, 2022
  • 1 location
Bone Microarchitectural Database Constitution From HR-pQCT Device in Clinical Situation Potentially Associated With Bone Loss

regions, and on the other hand, the thickness and cortical porosity and the number of trabecular, their orientation and distribution. Thus, the HR-pQCT allows realizing a virtual bone biopsy

bone mineral density
hyperparathyroidism
endocrine disorder
x-ray absorptiometry
osteoporosis
  • 24 views
  • 15 Feb, 2021
  • 1 location
The Effect of Semaglutide on Bone Turnover in Patients With Increased Risk of Bone Fracture

measured by bone markers in blood samples, bone scans, bone tissue tests (bone biopsy), and direct bone strength measured by microindentation at the start and end of the study.

  • 4 views
  • 07 Apr, 2021
  • 1 location
Effect of Multiple Perforations of the Sinus Floor on Bone Formation After Sinus Floor Elevation

. Thereafter, both sides are left to healing for 4-6 months until implant installation. At timepoint of implant installation, a bone biopsy will be collected to allow histological assessment of the grafted

Accepts healthy volunteers
  • 0 views
  • 24 May, 2022
  • 1 location
Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover

Osteoporosis affects 24.5% of women over 65 and results in fracture-related hospital admissions exceeding those of heart attacks, strokes and breast cancer combined. Current treatment options do not account for differences between age-related and estrogen deficiency related osteoporosis, because of the need for bone biopsies for determination. This study will …

hypercalcemia
cancer
calcium
risedronate
osteoporosis
  • 0 views
  • 25 May, 2022
  • 1 location
Evaluation and Treatment of Skeletal Diseases

will be collected for research use. Specimens will be obtained from bone removed during a patient s planned surgical procedure performed for medical care, or patients may be requested to have a bone

  • 11 views
  • 12 May, 2022
  • 1 location
UT Southwestern Diabetic Foot Ulcers (DFU) and Osteomyelitis (DFO) Recruitment Database, Data and Tissue Repository (DFUDatabase)

This will be a continuing, prospective study of diabetic foot ulcers and infections, risk factors and clinical outcomes and a limited data set conducted by the investigator through the establishment of a data and tissue repository in the uT Southwestern Department of Plastic Surgery. in addition, subjects consented for this …

diabetic foot
osteomyelitis
foot ulcer
diabetes
  • 104 views
  • 05 May, 2022
  • 2 locations
Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease

Background The rare disease melorheostosis causes bones to thicken. This may lead to pain, and can affect bones, joints, and muscles. Researchers want to learn more about the disease and how it progresses. Objective -To see what happens to people with melorheostosis over time and understand the causes of the …

electrical shock
x-rays
probe
urine test
melorheostosis
  • 15 views
  • 15 May, 2022
  • 1 location
Bone Density and Vascular Calcifications Evolution After Renal Transplant

The investigators project is based on: Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA); The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time; Longitudinal evaluation of nephrological …

  • 0 views
  • 24 May, 2022
  • 1 location