Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 22 clinical trials
Featured trial
UTI Study For Seniors

ARE YOU 60 YEARS OF AGE OR OLDER?People aged 60 years or older, with a history of UTI, are at an increased risk of developing a bloodstream infection

  • 19 Aug, 2021
  • 1 location
RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI (GAMECHANGER)

The purpose of this study is to determine whether a new antibiotic, Cefiderocol which works against a wide variety of gram negative bacteria, is equally effective as the antibiotics that are currently used as current standard of care.

  • 16 Jun, 2022
  • 13 locations
Efficacy and Safety of 7 Versus 14 Days of Antibiotic Treatment for Pseudomonas Aeruginosa Bacteraemia (SHORTEN2)

Phase IV, open-labeled, randomized and multicenter clinical trial to demonstrate the superiority of antibiotics with authorized indication for 7 days versus 14 days in the treatment of bloodstream infections produced by P. aeruginosa (BSI-PA).

  • 09 Jun, 2022
  • 1 location
Hydrochloric Acid Lock Therapy in Children With Cancer

Aim: This study will test whether treatment of central line associated bloodstream infection (CLABSI) with hydrochloric acid lock therapy (HALT) can significantly reduce the risk of treatment

  • 13 Jul, 2022
  • 1 location
The Use of Tetrasodium EDTA Catheter Lock Solution for Patients on Home Parenteral Nutrition:Ease of Use and Cost Analysis

ongoing nutrition. However, the presence of a CVC is associated with a risk of thrombosis and bloodstream infection. Many different types of catheter lock solutions have been used to mitigate these risks

  • 17 Jul, 2021
  • 1 location
CLiCK in the Critical Care Unit (CLiCK)

Insertion of a central venous access device (CVAD) allows clinicians to easily access the circulation of a patient to administer life-saving interventions. Due to their invasive nature, CVADss are prone to complications such as infection, bacterial biofilm production, and catheter occlusion due to a thrombus. A CVAD is placed in …

  • 29 Jul, 2022
  • 1 location
Infusion Set Replacement Intervals for Critically Ill Patients

This study aimed to evaluate the efficacy of 24-hour versus 96-hour infusion set replacement to prevent central line-associated bloodstream infection (CLABSI) in critically ill adults with

  • 11 May, 2022
  • 1 location
Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections (BGN)

Antimicrobial resistance is a major global problem, particularly in hospital-acquired infections (HAIs). Gram-negative bacilli (GNB), including Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii, are among the most common pathogens associated with multidrug resistance and HAIs. These bacteria are of special concern because few therapeutic options are available. Traditionally, the duration of …

septic shock
antimicrobial agent
  • 24 Mar, 2022
  • 4 locations
PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) (PETERPEN)

Data regarding optimal treatment for extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae blood-stream infection are lacking. Observational studies show conflicting results when comparing treatment with combination beta-lactam-beta-lactamase inhibitor and carbapenems. The investigators aim to evaluate the effect of definitive treatment with meropenem vs. piperacillin-tazobactam on the outcome of patients with bacteremia due …

beta-lactamase inhibitor
blood culture
  • 11 Aug, 2022
  • 7 locations
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants

The primary objectives of this study are: To assess the safety and tolerability of cefiderocol after single-dose administration in hospitalized paediatric participants 3 months to < 18 years of age with suspected or confirmed aerobic Gram-negative bacterial infections To assess the pharmacokinetics (PK) of cefiderocol after single-dose administration of cefiderocol …

renal function
abdominal infection
bacterial infection
  • 28 Apr, 2022
  • 9 locations