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Found 519 clinical trials
Efficacy of Nintedanib Per os as a Treatment for Epistaxis in HHT Disease.

recurrent in 90% of patients and associated with chronic and severe anemia in 2-10%. They also significantly reduce quality of life. Blood transfusions are sometimes required in 10-30% of patients

  • 0 views
  • 27 Jan, 2021
  • 10 locations
REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy

objectives of this study are to assess the following for REGN7257: Clinical response over time Maintenance of response Impact on transfusion requirements Effect on

  • 0 views
  • 17 Feb, 2021
  • 4 locations
Conservative Management of Morbidly Adherent Anterior Situated Placenta

morbidity and mortality can occur because of severe and sometimes life-threatening hemorrhage, which often requires blood transfusion also and rates of maternal death are increased for women with PAS

  • 0 views
  • 26 Jan, 2021
  • 1 location
B-Lynch Transverse Compression Suture Versus a Sandwich Technique (N&H Technique) for Complete Placenta Previa

increasing maternal age (6) It is considered one of the causes of the increased need for blood transfusion and cesarean hysterectomy. Various conservative measures have been developed to avoid

  • 0 views
  • 22 Jan, 2021
  • 1 location
CLOSED SUCTION DRAIN VS. NO DRAIN IN ADOLESCENTS UNDERGOING PEDICLE SCREW INSTRUMENTATION FOR IDIOPATHIC SCOLIOSIS (DAISY 2018). A Randomized Clinical Trial

for blood transfusion, need for re-operation, need for change in the dressings. Ethical aspects - Ethical committee approval will be obtained both in Finland and in Sweden. An informed consent

deep wound
spinal fusion
blood transfusion
deep surgical site infection
re-operation
  • 0 views
  • 22 Jan, 2021
  • 2 locations
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Background Diamond-Blackfan anemia (DBA) is treated with steroids. But some people cannot take steroids, or steroids don t work. Other patients must get blood

cell counts
  • 1 views
  • 27 Jan, 2021
  • 1 location
Evaluation of the Safety Tolerability Pharmacokinetics and Pharmacodynamics of PHI 101 for the Treatment of AML

cohorts planned) of each cohort are planned in Phase Ib based on study design. Phase Ib is also being conducted to assess anti-leukemia response, changes in transfusion requirements, and safety of PHI-101

  • 0 views
  • 30 Apr, 2021
Iron Balance Study of Deferasirox Deferoxamine and the Combination of Both

Subjects with thalassemia major require regular transfusion therapy to sustain life. The iron present in the transfused blood remains in the body where it can cause a variety of organ

desferal
blood transfusion
chelation therapy
deferasirox
iron overload
  • 28 views
  • 07 Nov, 2020
  • 1 location
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT

, immunosuppressant reduction, and platelet transfusion. Patients with viral infection may be treated with antiviral agents, but their efficacy is limited. When the HC was considered to be associated with aGVHD, some

tissue damage
clot formation
acute graft-versus-host disease
hematologic disorders
graft versus host disease
  • 0 views
  • 24 Jan, 2021
  • 1 location
Azithromycin in Post Diarrheal Haemolytic and Uremic Syndrome

, dialysis and red blood cells transfusions. Specific therapies used in D+HUS (plasma infusion, antithrombotic and anti inflammatory agents) failed to improve the course of D+HUS. The use of antibiotics

  • 0 views
  • 23 Jan, 2021
  • 1 location