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Found 520 clinical trials
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Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

myelodysplastic syndrome (mds)
anemia
myelodysplastic syndromes
anemia studies
aplastic anemia
  • 123 views
  • 22 Dec, 2020
  • 1 location
featured
Haplo-identical Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using Peripheral Blood Stem Cells and Post-Transplant Cyclophosphamide for GVHD Prophylaxis

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MD) cause serious blood problems. Stem cell transplants using bone marrow or blood plus chemotherapy can help. Researchers want to see if using peripheral blood stem cells (PBSCs) rather than bone marrow cells works too. PBSCs are easier to collect and have …

myelodysplastic syndrome (mds)
anemia
myelodysplastic syndromes
anemia studies
aplastic anemia
  • 57 views
  • 22 Dec, 2020
  • 1 location
featured
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of …

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia studies
aplastic anemia
  • 57 views
  • 22 Dec, 2020
  • 1 location
featured
Do You Have Osteoporosis?

Do You Have Osteoporosis?

  • 1122 views
  • 25 Mar, 2021
  • 1 location
Small-Volume Tubes to Reduce Anemia and Transfusion

STRATUS will evaluate the use of small-volume ("soft-draw") blood collection tubes for laboratory testing in reducing anemia and transfusion in intensive care unit patients without significant

  • 5 views
  • 24 Jan, 2021
  • 1 location
SAHaRA: A Randomized Controlled Trial

The SAHaRA trial will clarify the role of treating anemia with Red Blood Cell (RBC) transfusion in a unique and vulnerable patient population, and determine whether that impacts on functional

  • 173 views
  • 25 Jan, 2021
  • 15 locations
TXA in Spine Surgery

As tranexamic acid (TXA) becomes more prevalent, all patients are receiving the same dose and method of delivery regardless of their pre-operative risk of transfusion. Therefore, the aim of the

  • 0 views
  • 27 Jan, 2021
  • 1 location
Study to Evaluate the Efficacy Safety Tolerability Pharmacokinetics and Pharmacodynamics of IONIS TMPRSS6-LRx

The purpose is to evaluate the efficacy, safety, tolerability, pharmacokinetics and pharmacodynamics of IONIS TMPRSS6-LRx administered subcutaneously to participants with non-transfusion

  • 0 views
  • 28 Jan, 2021
  • 25 locations
  • 47 views
  • 02 May, 2021
  • 42 locations
Treatment of Hemochromatosis

hemochromatosis donors available for transfusion into other patients. Patients 15 years and older with diagnosed hemochromatosis or very high iron levels suggesting possible hemochromatosis may be eligible

  • 4 views
  • 14 Feb, 2021
  • 1 location