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Found 60 clinical trials
Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes

The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect on pediatric Type 1 diabetes.

type 1 diabetes mellitus
plasma glucose
diabetes
treatment regimen
insulin
  • 0 views
  • 08 Apr, 2022
  • 1 location
Effects of GRA in Patients With Type 1

This study will examine the effects a Glucagon Receptor Antagonist (GRA), has on Insulin Sensitivity, Cardiovascular risks (CVD), and Ketone body formation in participants with Type 1 diabetes. The participants will complete blood tests, tests to measure energy expenditure, CVD risks, and insulin resistance. These tests will be performed prior …

glucagon
treatment regimen
insulin resistance
diabetes
continuous glucose monitoring
  • 0 views
  • 07 Oct, 2021
  • 1 location
A Study on the Use of Real -Time Continuous Glucose Monitoring (RT-CGM) in Gestational Diabetes

The purpose of this study is to examine whether RT-CGM (real time continuous glucose monitoring) use improves glucose control, maternal outcomes, and fetal outcomes in patients diagnosed with gestational diabetes. Currently, there is very limited data on whether RT-CGM use helps patients diagnosed with gestational diabetes. By conducting this study, …

glucose tolerance test
oral glucose tolerance test
diabetes
hemoglobin a1c
continuous glucose monitoring
  • 0 views
  • 24 Jun, 2021
  • 1 location
Meals for Moms: Medically-Tailored Meals for Women Who Had Gestational Diabetes

The purpose of this research study is to test whether delivery of medically tailored meals (meals designed specifically to be healthy) can be used to help reduce high blood sugar after delivery of a baby. Participants will be recruited and consented during the third trimester of pregnancy but will begin …

  • 0 views
  • 10 May, 2022
  • 1 location
Preoperative Nutritional Optimization and Physical Exercise for Patients Scheduled for Elective Implantation for a Left-Ventricular Assist Device (PROPER-LVAD)

This is a pilot, randomized, multicenter interventional trial of a combined preoperative oral nutritional support (ONS) and physical exercise therapy in patients planned for elective implantation of a left-ventricular assist device (LVAD). This pilot study pursues to demonstrate the feasibility and safety of a study protocol to optimize the patients' …

  • 0 views
  • 09 Jun, 2022
  • 2 locations
Two Bag System for Diabetic Ketoacidosis (2BagDKA)

This is a study investigating the best way to treat diabetic ketoacidosis (DKA) with intravenous (IV) fluids in the hospital. The purpose of this study is to determine whether the "two bag" system of administering IV fluids for the treatment of adults with DKA leads to a shorter time requiring …

diabetic ketoacidosis
insulin
sugars
  • 4 views
  • 14 Feb, 2022
  • 1 location
Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome

Arterial disease is the leading cause of morbidity/mortality in Metabolic syndrome (MetS). This occurs early as evidenced by arterial dysfunction that, in turn, raises blood pressure and glucose. Health organizations recommend exercise in an intensity based manner to promote cardiovascular adaptation and prevent disease. Metformin is a common anti-diabetes medication …

metformin
diabetes
body mass index
hdl cholesterol
fasting
  • 11 views
  • 24 Mar, 2022
  • 2 locations
Insulin Resistance Following ADT for Prostate CA

Prostate cancer is the most common cancer in men in the United States. Suppression of male hormone levels by using GnRH agonist ("hormone blocking therapy") for a few years is routinely used to treat prostate cancer. While the treatment is very effective, it decreases muscle mass and increases fat mass. …

  • 0 views
  • 22 Apr, 2022
  • 1 location
Pragmatic Lifestyle Pregnancy and Post Pregnancy Intervention for Overweight Women With Gestational Diabetes Mellitus

This study is designed to determine if a postnatal lifestyle intervention will lead to weight reduction over a 12 month period post-delivery in women who have been diagnosed with gestational diabetes mellitus and who have a BMI greater that 25 compared to women who receive routine care.

self-monitoring of blood glucose
plasma glucose
diabetes
weight control
a 12
  • 7 views
  • 26 Jan, 2021
  • 1 location
Investigating the Role of the Polyol Pathway in the Central Nervous System

Patients will undergo magnetic resonance spectroscopy (MRS) scanning to noninvasively measure intracerebral and plasma metabolite levels at baseline and following 2 and 4 hours of hyperglycemia. Subjects will also undergo a lumbar puncture at a separate occasion to assess cerebrospinal fluid levels of metabolites.

glycosylated hemoglobin
metformin
hemoglobin a1c
sulfonylurea
insulin
  • 0 views
  • 11 Jul, 2021
  • 1 location