Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 67 clinical trials
Safety and Feasibility Study of Methylene Blue Photodynamic Therapy to Sterilize Deep Tissue Abscess Cavities

The objectives of this Phase 1 study are to evaluate the safety and feasibility of methylene-blue-mediated photodynamic therapy (MB-PDT) performed at the time of abscess drainage to treat deep tissue abscesses. Safety will be evaluated by physical examination and imaging and laboratory studies in order to identify adverse events that …

cavities
drainage
methylene
  • 26 views
  • 05 Apr, 2022
  • 1 location
Treatment of Ocular Demodex Infestation With Topical Ivermectin Cream 1%

Patients with Demodex infestation of the eyelids will have the sleeves from both eyes cleaned off with microblepharoexfoliation. Afterwards, one eye will be randomly selected for treatment with topical ivermectin 1% cream. The treatment will be repeated on that eye 2 weeks later. Afterwards, the patients will present monthly for …

Accepts healthy volunteers
  • 12 views
  • 24 Mar, 2022
  • 1 location
A Phase 3, Double-blind, Randomized Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK Inhibitor Therapy and Who Require Red Blood Cell Transfusions (INDEPENDENCE)

) and anemia on concomitant Janus kinase 2 (JAK2) inhibitor therapy and who require red blood cell count (RBC) transfusions. The study is divided into Screening Period, a Treatment Phase

vasectomy
anemia
cancer
bilateral oophorectomy
  • 29 views
  • 22 Sep, 2022
  • 136 locations
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children. The cancer comes from a cell in the blood called a lymphocyte. Normal lymphocytes are produced in the bone marrow (along with other blood cells) and help fight infections. In ALL, the cancerous lymphocytes are called lymphoblasts. They …

mercaptopurine
methotrexate
conjugated bilirubin
b-cell acute lymphoblastic leukemia
lymphoblasts
  • 26 views
  • 20 Jun, 2022
  • 9 locations
Elotuzumab for the Treatment of JAK2-Mutated Myelofibrosis

This phase II trial investigates how well elotuzumab works in treating patients with JAK2-mutated myelofibrosis. Elotuzumab may help to control myelofibrosis and/or help to improve blood cell

  • 0 views
  • 01 Mar, 2021
  • 1 location
Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates

Acute respiratory distress syndrome (ARDS) in neonates has been defined in 2017. The death rate is over 50%.There are no special treatments for acute respiratory distress syndrome.

acute respiratory distress
  • 22 views
  • 24 Feb, 2021
  • 1 location
Bcl-2 Inhibitors Combined With Azacytidine and Chemotherapy in Elderly Patients With Previously Untreated AML

recovery of blood cell count (CR/ CRi) were used as the primary endpoints, and time to response (TTR), duration of response (DOR), mortality, and recurrence rate were used as secondary endpoints,and the

cladribine
cytarabine
venetoclax
remission
azacitidine
  • 0 views
  • 09 May, 2022
  • 1 location
Blue Light Therapy in Reducing Inflammation During Sepsis

. The outcome of interest is change in the inflammatory response after surgery for appendicitis or diverticulitis as measured by the following parameters: white blood cell count, heart rate, the

white blood cell count
diverticulitis
pneumonia
sepsis
appendectomy
  • 119 views
  • 10 Mar, 2022
  • 1 location
A Phase I Study of MozobilTM in the Treatment of Patients With WHIMS

neutropenia. Objectives To evaluate whether Mozobil is safe and effective to treat neutropenia (low white blood cell count) in patients with WHIMS

white blood cell count
granulocyte colony stimulating factor
neutropenia
warts
bone marrow transplant
  • 112 views
  • 14 Sep, 2022
  • 1 location
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

their white blood cell count. This will be a shot or injection under the skin. Participants will recover in the hospital for 1-2 weeks. They will have lab and blood tests. Participants

antibiotic
leucovorin
cancer chemotherapy
irinotecan
gemcitabine
  • 31 views
  • 14 Sep, 2022
  • 1 location