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Found 21 clinical trials
Efficacy of Metformin for Sputum Conversion in Patients With Active Pulmonary Tuberculosis

This study was a randomized controlled trial studying about acid-fast bacillus sputum conversion ratio from positive to negative of pulmonary tuberculosis patients between metformin with pulmonary tuberculosis standard treatment group and placebo drug with pulmonary tuberculosis standard treatment.

  • 23 Mar, 2022
  • 1 location
Influence of Dexmedetomidine or Propofol on ICU Delirium

In this randomized study, the investigators aim to test the hypothesis that the reinstitution of a normal circadian rhythm by continuous infusions of dexmedetomidine compared to propofol between 8pm and 6am after diagnosis of hyperactive or mixed delirium, decreases the duration of delirium. The infusions might have to be repeated …

  • 24 Apr, 2022
  • 1 location
Selinexor Treatment for Multiple Myeloma Patients Who Are Refractory to Lenalidomide-containing Therapy.

This is a pilot study evaluating the safety and efficacy of selinexor among multiple myeloma (MM) patients that are refractory to lenalidomide-containing regimens with or without steroids.

  • 06 May, 2022
  • 1 location
Topical Vancomycin Over Sternal Edge in Cardiac Surgery

This is a single-blind 1:1 randomized controlled trial based on the hypothesis that topical application of vancomycin paste over sternum edge is safe and can reduce sternal wound infection after elective cardiac surgery. Vancomycin paste will be prepared using 2.5 g of vancomycin mixed with 2 ml normal saline. Vancomycin …

  • 12 Sep, 2021
  • 1 location
BUN/Cr-based Hydration Therapy to Improve Outcome of Patients With Acute Ischemic Stroke

acute ischemic stroke-version 2. II. Indication: We use blood urea nitrogen (BUN)/blood creatinine (Cr) ratio15 as a dehydration biomarker. This clinical trial aims to determine if more

  • 24 Nov, 2021
  • 1 location
Glutathione in Mild Cognitive Impairment

Elderly humans have an increased risk of dementia which begins as mild defects in memory called mild cognitive impairment. Glutathione (GSH), a key endogenous antioxidant has been linked to cognition. This exploratory study will investigate mechanisms linked to GSH for cognitive impairment (and improvement) by studying humans with mild cognitive …

  • 25 Mar, 2022
  • 1 location
Clinical Efficacy of Megadose Vitamin C in Sepsis (CEMVIS)

In this multicenter, randomized, single-blind, placebo-controlled clinical trial. Patients will be randomly assigned to receive Vitamin C or placebo for 4 days or until ICU discharge (whatever come first). The primary outcome is 28-day all-cause mortality.

  • 06 Mar, 2022
  • 1 location
Targeted vs Standard Fortification of Breast Milk

BACKGROUND Human milk (HM) is recommended for all very low birth infants (VLBW)). Breast-milk is highly variable in nutrient content, failing to meet the nutritional demands of VLBW. Fortification of HM is recommended to prevent extra-uterine growth retardation and associated poor neurodevelopmental outcome. However, standard fortification with fixed dose multicomponent …

very low birth weight
necrotizing enterocolitis
bronchopulmonary dysplasia
  • 26 Mar, 2022
  • 1 location
Observatory on Impact of Life Styles on Health Outcomes

The present is an observational study conducted on the general population in villages of Southern Italy every year during the world hypertension day. So far, A total of 412 persons (193 males and 219 female, 14-85 years) were recruited during the XI and XII World Hypertension Day (2015 and 2016). …

  • 21 Jan, 2021
  • 1 location
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing

The purpose of this research is to understand how to apply cardiac magnetic resonance imaging (CMR) to women with small artery heart disease by looking at the CMRs of women without heart disease. The investigators will study 40 women with no heart disease to learn more about the usefulness of …

Accepts healthy volunteers
  • 23 Jan, 2022
  • 1 location