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Found 499 clinical trials
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Cross-sectional survey: Female opinion on receiving transfusion of O positive blood in trauma

, would you want a blood transfusion, if by receiving blood there is a risk to current or future pregnancies.Participants would complete a one-time survey. There are no study

  • 0 views
  • 19 Mar, 2021
  • 1 location
featured
An observational, multi-center study to evaluate the safety of deferasirox in the treatment of pediatric patients with non-transfusion-dependent iron overload.

An observational, multi-center study to evaluate the safety of deferasirox in the treatment of pediatric patients with non-transfusion-dependent iron overload.

  • 324 views
  • 25 Mar, 2021
  • 1 location
featured
Eltrombopag for People With Fanconi Anemia

Fanconi anemia is a genetic disease. Some people with it have reduced blood cell counts. This means their bone marrow no longer works properly. These people may need blood transfusions for anemia

anemia
anemia studies
fanconi's syndrome
fanconi's anemia
  • 91 views
  • 22 Dec, 2020
  • 1 location
featured
A Phase 1/2 Open-Label, Multicenter Study of INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

combination with ruxolitinib in participants with MF who are transfusion-dependent or presenting with symptomatic anemia. INCB000928 tablets will be administered orally at a starting dose of 50 mg QD in

anemia
  • 67 views
  • 05 Oct, 2020
  • 1 location
featured
COMMANDS - Myelodysplastic Syndromes (MDS) - ACE536-MDS-002 - Australia  

) versus epoetin alfa for the treatment of anemia due to IPSS-R very low, low or intermediate risk MDS in ESA naïve subjects who require RBC transfusions. The study is divided into the Screening

vasectomy
cancer
epoetin alfa
erythropoietin
  • 53 views
  • 26 Mar, 2021
  • 7 locations
featured
COMMANDS - Myelodysplastic Syndromes (MDS) - ACE536-MDS-002 - US  

luspatercept (ACE-536) versus epoetin alfa for the treatment of anemia due to IPSS-R very low, low or intermediate risk MDS in ESA naïve subjects who require RBC transfusions.   The

vasectomy
cancer
epoetin alfa
erythropoietin
  • 5134 views
  • 20 Jul, 2021
  • 14 locations
featured
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

>Eligibility: Adults ages 18-80 of African descent. They may have sickle cell disease or not. They must not have had a transfusion recently or have a known deficiency of pyruvate kinase

sickle cell disease
red blood cell disorder
sickle cell anemia
  • 48 views
  • 22 Dec, 2020
  • 1 location
featured
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Donor cells infused through their central line Transfusions After about 30 days, recipients will leave the hospital. They must stay near NIH for 3 months after the

cell transplantation
sickle cell disease
red blood cell disorder
stroke
  • 57 views
  • 22 Dec, 2020
  • 1 location
featured
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

medicines, for transfusions of red blood cells and platelets, and for collecting blood samples. Preparatory chemotherapy (fludarabine, cyclophosphamide and anti-thymocyte globulin) and total body

myelodysplastic syndrome (mds)
anemia
anemia studies
myelodysplastic syndromes
aplastic anemia
  • 48 views
  • 22 Dec, 2020
  • 1 location
featured
A Randomized Trial of Sirolimus (Rapamune) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Background: People with severe aplastic anemia (SAA) do not make enough red and white blood cells, and/or platelets. Their body's immune system stops the bone marrow from making these cells. The treatment cyclosporine leads to better blood counts. But when this treatment is stopped, the disease may return in 1 …

myelodysplastic syndrome (mds)
anemia
anemia studies
myelodysplastic syndromes
aplastic anemia
  • 61 views
  • 22 Dec, 2020
  • 1 location