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Found 8 clinical trials
Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD

This study aims to investigate whether a 7-day dietary high protein supplementation of 90 grams per day increases plasma sodium levels in hyponatremic patients with chronic SIAD. Enrolled patients will receive first dietary high protein supplementation for one week. After a wash-out phase of at least one week, the patients …

  • 2 views
  • 20 Oct, 2021
  • 1 location
Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia (HIT)

Hyponatremia is the most common electrolyte disorder with a prevalence of up to 30% in hospitalized patients. While treatment of acute hyponatremia with severe clinical symptoms due to cerebral edema is undisputed and straightforward, hyponatremia in general is usually considered asymptomatic or not clinically relevant. Accordingly, a recent observational study …

chronic hyponatremia
electrolytes
hyponatremic
edema
  • 55 views
  • 14 Feb, 2022
  • 1 location
Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage (NAT-URE)

Hyponatremia is defined as a plasma sodium concentration below 135 mmol / L. This is a common occurrence (20-50%) during subarachnoid hemorrhage (SAH). Its appearance is often associated with vasospasm. It is associated with an increase in morbidity and mortality linked to induced neurological disorders. Hyponatremia is caused by two …

siadh
serum sodium
  • 55 views
  • 25 May, 2022
  • 1 location
Urea for Chronic Hyponatremia

This study is examining how a dietary supplement called urea can be used to treat low blood sodium level. Low blood sodium level is a common problem and some studies show that many patients with

chronic hyponatremia
blood sodium
siadh
osmolality
  • 0 views
  • 08 Jun, 2022
  • 1 location
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) (DHAPS)

Hyponatremia is defined as sodium below the normal range of 135-145. Symptomatically, it can cause patients to experience a wide range of symptoms including lethargy, headache, nausea, vomiting and in severe cases coma and even death. The goal of this study is to prospectively compare two approaches to the postoperative …

hormone secreting
pituitary tumor
nausea
headache
gonadotropin
  • 262 views
  • 20 Apr, 2022
  • 1 location
Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia - a Multicentric Randomized Double-blind Placebo-controlled Trial (the EMPOWER Study) (EMPOWER)

Hyponatremia is the most common electrolyte derangement occurring in hospitalized patients. It is usually classified as hypovolemic, euvolemic or hypervolemic. The most common aetiology of euvolemic hyponatremia is the syndrome of inappropriate antidiuresis (SIAD). Hypervolemic hyponatremia is common in patients with congestive heart failure (CHF) (10-27%) and liver cirrhosis (up …

heparin
diabetes
fluid restriction
vasopressin
heart failure
  • 0 views
  • 15 Sep, 2022
  • 3 locations
Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage (CRYSTALLBrain)

type of infusion fluid significantly influences blood sodium content. Hence, this study evaluated whether the sodium content of the infusion solution impacts mortality and morbidity in patients with

  • 0 views
  • 08 Jun, 2022
  • 1 location
Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients (BONA)

In this study, the possible role of serum sodium concentration and its changes on bone markers in hospitalized, hyponatremic patients is determined. Therefore, it is investigated whether in hospitalized, hyponatremic patients the level of carboxy-terminal collagen crosslinks (CTX) is modified by changes in plasma sodium concentration, independently from the aetiology …

serum sodium
hyponatremic
osmolality
  • 7 views
  • 24 Feb, 2022
  • 1 location