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Found 8 clinical trials
EG-70 in NMIBC Patients Who Are BCG-Unresponsive and High-Risk NMIBC Patients Who Have Been Incompletely Treated With BCG or Are BCG-Naïve (LEGEND STUDY)

This open-label, multicenter study will evaluate the safety and efficacy of intravesical administration of EG-70 and its effect on bladder tumors in patients with NMIBC who have failed BCG therapy and are recommended for radical cystectomy or high-risk NMIBC patients who are BCG-naïve or have received incomplete BCG treatment. This …

  • 23 May, 2022
  • 8 locations
Atezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle Invasive Bladder Cancer Patients (ALBAN)

This is an open-label, randomized, multicentric study in patients with high-risk non-muscle invasive bladder cancer who had never received BCG for this disease. The objective is to evaluate the efficacy of atezolizumab as measured by recurrence-free survival.

gilbert's syndrome
invasive bladder cancer
bladder instillation
  • 16 Jun, 2022
  • 32 locations
Does Bladder Instillation Reduce Time to Discharge After Sling Surgery

The purpose of this randomized control trial study is to determine if intraoperative bladder instillation of fluid decreases the time to discharge after having an outpatient mid-urethral sling

sling procedure
  • 05 Mar, 2022
  • 1 location
Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment

This study will evaluate the safety of bladder instillation with Camrelizumab and compare to the efficacy of intravesical therapy with intravenous therapy using Camrelizumab in patients with

radical cystectomy
invasive bladder cancer
neutrophil count
bladder instillation
  • 18 Oct, 2021
  • 3 locations
Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC

primary objective of this trial is to increase the rate of pathologic complete remission (pCR) at the time of radical cystectomy by the combination of local bladder instillation with Bacillus Calmette

intravesical bcg
radical cystectomy
invasive bladder cancer
bladder tumor
  • 04 Oct, 2022
  • 9 locations
Recurrent Urinary Tract Infections and Heparin (RUTIH Trial)

Urinary Tract Infections (UTIs) are the second most common infection in the body. UTIs account for five percent of all visits to primary care physicians. Many women who have had a UTI will develop recurring urinary tract infections. Recent studies suggest that some women who suffer from recurrent UTIs have …

  • 09 Jun, 2022
  • 1 location
Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury

A non-randomized study evaluating the efficacy of intravesical gentamicin on the occurrence rate of urinary tract infections and bladder complications in patients after spinal cord injury (SCI), and to assess its effectiveness in promoting overall quality of life (QOL), community living, and participation.

urinary tract infection
spinal cord disorder
neurogenic bladder
incomplete spinal cord injury
bladder instillations
  • 10 May, 2022
  • 1 location
Flemish Databank for Urothelial Cancer

The goal of the Flemish Databank for Urothelial Cancer is to collect clinical and pathological data of patients treated for urothelial cancer (UC).

transurethral resection
radical cystectomy
  • 09 Feb, 2022
  • 1 location