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Found 14 clinical trials
Bivalirudin in Acute Myocardial Infarction

The purpose of the study is to evaluate the efficacy and safety of bivalirudin in AMI patients with DES. This is a prospective, randomized, single-blind, active drug controlled

bivalirudin
percutaneous coronary intervention
chest pain
stemi
bundle branch block
  • 0 views
  • 08 Nov, 2020
  • 1 location
Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During Emergency PCI

STEMI treated with emergency PCI. A total of 6000 STEMI patients will be enrolled and randomly assigned to receive bivalirudin or heparin during emergency PCI in a 1:1 ratio. This study will provide key

antithrombotic agents
heparin
aspirin
clopidogrel
ticagrelor
  • 0 views
  • 25 Oct, 2020
  • 1 location
EArly Discharge After Transradial Stenting of CoronarY Arteries in High-Risk Patients of Bleeding

> With femoral approach, bivalirudin compared to heparin glycoproteins IIb-IIIa has been associated with a significant reduction in access-site and non-access site related bleeding. In a post

heparin
bivalirudin
  • 31 views
  • 08 Nov, 2020
  • 1 location
Comparison of Anticoagulation Prolongation vs. no Anticoagulation in STEMI Patients After Primary PCI

prolonged for at least 48 hours after the procedure vs. no prolongation of anticoagulation after procedure in patients with STEMI treated with bivalirudin during PPCI (primary hypothesis). When allocated to

heparin
enoxaparin
stemi
  • 0 views
  • 17 Jan, 2021
  • 1 location
Reduce Bolus Injection of Bivalirudin

There are fewer studies on the bleeding risk of the currently administered bivalirudin bolus injection dose and the safety of bivalirudin in patients with CKD. A non-inferiority, randomized

  • 0 views
  • 08 Jan, 2021
  • 1 location
Peri-Procedural Myocardial Infarction Platelet Reactivity Thrombin Generation and Clot Strength: Differential Effects of Eptifibatide + Bivalirudin Versus Bivalirudin

stent implantation. The first group will be on a regimen of high-dose clopidogrel used in combination with bivalirudin plus eptifibatide, and the second group will be on a regimen of high-dose

bivalirudin
infarct
clopidogrel
clot
platelet aggregation
  • 6 views
  • 07 Nov, 2020
  • 1 location
Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.

The study is an investigator-sponsored, prospective, multicenter, randomized, open-label study designed to compare efficacy and safety between bivalirudin and heparin in elderly patients with

percutaneous coronary intervention
heparin
bivalirudin
acute coronary syndrome
  • 1 views
  • 12 Aug, 2019
  • 1 location
Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric ECMO

receive unfractionated heparin and the other arm will receive bivalirudin. There will be 15 patients in each arm for a total of 30 patients. Primary aim will be to compare the efficacy of

  • 28 views
  • 15 Oct, 2020
  • 1 location
Comparing Bivalirudin Versus Heparin/ GP IIB/IIA in Patients Undergoing PCI

The purpose of this study is to compare the rates of vascular related complications in patients undergoing percutaneous coronary intervention assigned to one of two arms: 1) bivalirudin

heparin
angina pectoris
bypass graft
bivalirudin
unstable angina
  • 11 views
  • 07 Nov, 2020
  • 1 location
Anticoagulation in Patients Suffering From COVID-19 Disease The ANTI-CO Trial

in the pulmonary bloodstream. Recently we implemented an algorithm applying higher doses of heparins (LMWH). However, this approach could not inhibit clotformation enough. Bivalirudin could prevent

  • 0 views
  • 01 Jul, 2020
  • 1 location