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Found 263 clinical trials
Hematopoietic Stem Cell Transplant Survivors Study (HTSS Study) (HTSS)

The investigators hope to find the proof of principle concept from this pilot study so that the investigators can design a clinical trial based on the results of the explanatory hypothesis.

quercetin
  • 652 views
  • 04 Oct, 2022
  • 1 location
Venetoclax and Decitabin Based Conditioning Regimen Followed With Post-HSCT Decitabin Maintenance Therapy in TP53 Mutant AML/MDS Patients

This study aims to evaluate the effectiveness and safety of Venetoclax and Decitabin based conditioning regimen followed with post-HSCT Decitabin maintenance therapy in TP53 mutant AML/MDS Patients.

  • 0 views
  • 07 Oct, 2022
  • 1 location
Saxon SARS-CoV-2 Infection and Vaccination Study in Dialysis Patients, Solid Organ Recipients and Staff (DIA-Vacc)

To investigate short- (3 and 8 weeks) and long-term (6, 9, 12, and 18 months) immune protection or response at the humoral and cellular levels before and after SARS-CoV-2 infection or vaccination in patients with moderately reduced immune status (dialysis patients) and severely reduced immune status (organ transplant recipients, mostly …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell Transplantation

Background People who have had an allogeneic hematopoietic stem cell transplant (HCT) have bone marrow or an immune system that is damaged. They get stem cells from a donor who is a relative. Researchers want to study stem cell donors and recipients to learn about the long-term effects of HCT. …

cancer
allogeneic hematopoietic stem cell transplant
blood test
Accepts healthy volunteers
  • 30 views
  • 28 Oct, 2022
  • 1 location
Lipopolysaccharide Metabolism and Identification of Potential Biomarkers Predictive of Graft-versus-host Disease After Allogeneic Stem Cell Transplantation (MetAlloLip)

This study is designed to assess the hypothesis that the lipopolysaccharide (LPS) activity index can be quantified early after transplantation, as well as the the PhosphoLipid Transfer Protein (PLTP) activity and these both biological variables are independent variables for predicting the risk of severe Graft versus Host Disease (GVHD).

remission
hematologic malignancy
allogeneic hematopoietic stem cell transplant
cancer
cell transplantation
  • 1 views
  • 22 Apr, 2022
  • 1 location
Haplo SCT vs Haplo-cord SCT for Patients With Hematological Disorders

Patients who have hematological disorders and will undergo haplo-identical donor stem cell transplantation (haplo SCT) are candidates of this trial. Participants will randomized into two arms: Arm A will undergo a typical haplo SCT, while Arm B will receive an co-infusion of an unrelated cord blood unit (haplo-cord SCT) in …

cell transplantation
hematologic disorder
  • 15 views
  • 15 Feb, 2022
  • 1 location
Nutritional Status of Patients After Hematopoietic Stem Cell Transplantation

The main objectives of this study were :(1) to comprehensively and systematically evaluate the nutritional status of patients after hematopoietic stem cell transplantation. (2) to explore the effect of nutritional factors on the prognosis of patients treated by hematopoietic stem cell transplantation.

  • 0 views
  • 26 Apr, 2022
  • 1 location
Impact of Prehabilitation in Oncology Via Exercise- Bone Marrow Transplant (IMPROVE-BMT)

The purpose of this study is to determine whether patients are able to participate in a prehabilitation program (prior to the beginning of treatment) which includes: (1) a home-based exercise program or (2) just a prehabilitation education session.

remission
hodgkin's disease
leukemia
chronic myeloid leukemia
bone marrow transplant
  • 9 views
  • 09 Apr, 2022
  • 1 location
Study on the Relationship of Arterial-venous Oxygen Difference and Postoperative Complications After Cardiac Surgery.

Avoidance of unnecessary blood transfusions has always been a focus of clinical research. The rate of perioperative red blood cell transfusion in patients undergoing cardiac surgery under cardiopulmonary bypass reaches between 50-70%, and the intraoperative red blood cell transfusion rate is 30-50%. Regarding whether and when to perform a blood …

oximetry
cardiovascular surgery
red blood cell transfusion
oxygen saturation
cardiopulmonary bypass
  • 0 views
  • 22 Oct, 2021
  • 1 location
Modification of the Human Colon and Oral Microbiome by Allogenic HSCT

Allogenic HSCT brings significant changes in biodiversity and composition of the gut microbiome through antibiotic usage, the mucosal damage due to the chemo- and radiotherapy toxicity; compromised oral nutritional intake and graft-versus-host disease with gut damage as the complication. Aim of the study is to investigate the composition of the …

graft versus host disease
microbiota
  • 0 views
  • 08 Feb, 2022
  • 1 location