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Found 272 clinical trials
Featured trial
Advanced Colorectal or Lung Cancer Screening

Advanced Colorectal or Lung Cancer Screening

  • 180 views
  • 25 Mar, 2021
  • 1 location
Trifluridine/Tipiracil (TAS-102) With or Without Thalidomide for the Treatment of Metastatic Colorectal Cancer

Thalidomide has both anti-angiogenesis and antiemetic effects, and its combined use with TAS-102 may reduce the gastrointestinal reactions associated with TAS-102, while enhancing antitumor efficacy and reducing the side effects of chemotherapy, and its cost is significantly lower than that of bevacizumab, which has higher pharmacoeconomics and greater clinical research …

  • 0 views
  • 15 Mar, 2022
Efficacy and Safety of On-demand and Continuous Administration of Nasal Spray in the Treatment of Allergic Rhinitis

WHO recommend to divide AR into 4 subgroups according to the symptom frequency (intermittent or persistent) and severity (mild or moderate-to-severe). For the persistent moderate-to-severe AR subgroup, the guideline suggests to treat with intranasal corticosteroid (INS) plus antihistamines (AH1) for 2-4 weeks. If the symptom is controlled then degrade the …

  • 4 views
  • 11 May, 2022
  • 1 location
Breast Cancer: Axillary Conservation After Neoadjuvant Chemotherapy in Micro Metastatic Sentinel Lymph Nodes. (NEONOD2)

Italian multicentric non inferiority clinical study to verify whether the omission of axillary lymph node intervention in patients with SLN (Sentinel Lymph Nodes) ypN1mi after NAC (Neo Adiuvant Chemotherapy) does not lead to a significant deterioration in survival or in the risk of regional or distant recurrence, compared to patients …

carcinoma
breast carcinoma
metastasis
axillary lymph node dissection
invasive breast cancer
  • 2 views
  • 12 Feb, 2022
  • 1 location
Pilot Study of the Feasibility and Safety of a Personalized Peptide Vaccine in Patients With Advanced Pancreatic Ductal Adenocarcinoma or Colorectal Adenocarcinoma

usually cannot be cured or controlled with treatment (advanced). Personalized peptide vaccine is a vaccine developed from patient's own tumor cells and blood in order to use as a biological therapy

measurable disease
adenocarcinoma
tumor marker
solid tumors
vasectomy
  • 11 views
  • 18 Sep, 2022
  • 1 location
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

moderate psoriasis. Eligibility People ages 18-80 with mild to moderate active psoriasis not currently treated with biological therapy Design

Accepts healthy volunteers
vitamins
niacin
body mass index
  • 83 views
  • 16 Sep, 2022
  • 1 location
Clinical Study Comparing Different Strategies to Increase Adherence to Oral Therapies in Oncohematology

This is a multicenter, interventional, non-pharmacological study on a app for oral anticancer therapy management. A total of 124 patients will be considered. Patients will be randomized 1:1 to one of the following interventions: electronic diary B. paper diary The primary aim of the study is to assess the effectiveness …

immunostimulants
  • 0 views
  • 06 Nov, 2021
  • 2 locations
A Comparative Study of MRI, US and CE for Assessing Treatment Response in Known Crohn's Disease

The aim of this study is to evaluate non-invasive imaging techniques for assessing treatment response in known Crohn's disease. Comparing imaging modalities: The applicability of small bowel colon capsule endoscopy (SBCCE), magnetic resonance enterocolonography (MREC) and ultrasound (US) for diagnosing ulcer healing after medical treatment in patients with symptomatic Crohn's …

capsule endoscopy
endoscopy
crohn's disease
ulceration
corticosteroids
  • 5 views
  • 26 Feb, 2022
  • 1 location
Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study (CABATEN)

CABATEN is a multicohort phase II study of cabozantinib plus atezolizumab in advanced and progressive tumors from endocrine system. The primary objective is to assess the efficacy of cabozantinib plus atezolizumab combination by means of radiological objective response rate (ORR) evaluated following RECIST v1.1 criteria in advanced endocrine tumors. Endocrine …

measurable disease
paraganglioma
growth factors
adrenaline
basic fibroblast growth factor
  • 0 views
  • 24 Mar, 2022
  • 14 locations
Biologic Therapy to Prevent Osteoarthritis After ACL Injury

Anterior cruciate ligament (ACL) injuries are extremely common. On average, 50% of individuals suffering an ACL injury will develop radiographic osteoarthritis (OA) 10 to 20 years after injury. Unfortunately, ACL reconstruction does not prevent risk of future OA. Interleukin-1 (IL-1) levels in the human knee joint increase transiently after an …

autograft
arthritis
interleukin-1
Accepts healthy volunteers
breakdown
  • 0 views
  • 11 Jul, 2022
  • 1 location