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Found 199 clinical trials
Liposomal Irinotecan Fluorouracil Leucovorin Calcium and Rucaparib in Treating Patients With Metastatic Pancreatic Colorectal Gastroesophageal or Biliary Cancer

treating patients with pancreatic, colorectal, gastroesophageal, or biliary cancer that has spread to other places in the body (metastatic). Drugs used in chemotherapy, such as liposomal irinotecan

homologous recombination deficiency
metastatic adenocarcinoma
irinotecan
platelet count
rucaparib
  • 8 views
  • 16 May, 2021
  • 4 locations
Programmed Death Ligand (PD-L1) Combined With Chemotherapy for Patients With BTC

chemotherapies in the treatment of participants with previously untreated locally advanced or metastatic biliary tract cancer. The primary hypothesis of this study is that participants will have a longer

systemic therapy
oxaliplatin
metastatic biliary tract carcinoma
biliary tract cancer
gemcitabine
  • 8 views
  • 29 Mar, 2021
  • 1 location
Study of TRIFLURIDINE/TIPIRACIL in Previously Treated Cholangiocarcinoma

This is a multi-centre, open-label, single arm phase 2 study to assess the efficacy of TRIFLURIDINE/TIPIRACIL, in patients with advanced cholangiocarcinoma as measured by median progression-free survival (PFS). This study will enroll a total of 47 patients over a 12-month period, according to a two stage enrollment design. Nine patients …

capecitabine
platelet count
kidney function tests
liver metastasis
ct scan
  • 58 views
  • 25 Mar, 2021
  • 1 location
Apatinib for Advanced Biliary Carcinoma

This is a phase II open-label, one-arm, single-center study of apatinib for eligible patients with advanced biliary tract carcinoma after the first-line treatment failure. A total of 55 patients is planned for enrollment. The time for enrollment is from Nov 2017 to Nov 2020, the the follow-up will be ended …

apatinib
platelet count
mitomycin
measurable disease
carcinoma
  • 15 views
  • 22 Jan, 2021
Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemotherapy

first-line chemotherapy (experimental arm) over standard oncology care only (standard arm), in patients with metastatic upper gastrointestinal cancers (gastric cancer, pancreatic cancer, biliary tract

erbb2
gastric cancer
metastasis
gastrointestinal cancer
cancer chemotherapy
  • 25 views
  • 24 Jan, 2021
  • 29 locations
CT Perfusion Scans in Detecting Changes in Blood Flow to the Liver After Portal Vein Embolization

This trial studies the use of computed tomography (CT) perfusion scans in detecting changes in blood flow to the liver after portal vein embolization in patients with liver cancer. CT perfusion scans use a standard contrast drug given by vein to measure blood flow to the liver. CT perfusion scans …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Irreversible Electroporation(IRE) For Unresectable Gallbladder Neoplasms

The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for unresectable Gallbladder Neoplasms.

anticoagulants
platelet count
gallbladder neoplasms
  • 36 views
  • 23 Jan, 2021
  • 1 location
Comparing the Current Hydration Regimen for the ABC02 Chemotherapy Regimen Versus a Shorter Hydration

This is an open label study for any patients with a bile duct cancer or gallbladder cancer, who will be treated with gemcitabine and cisplatin chemotherapy (the ABC02 regime). Patients recruited onto this study will have a reduction of their hydration time and be given Akynzeo as an anti-sickness drug, …

renal function
carcinoma
gemcitabine
cholangiocarcinoma
cancer
  • 0 views
  • 13 Mar, 2021
  • 1 location
The Effect in Wedge Resection and IVb/V Resection of the Liver for Gallbladder Cancer

The extent of hepatic resection for gallbladder cancer can be done from a wedge resection to 4b/5 bisegmentectomy. This study aims to compare the recurrence rates and survival rates between wedge resection group and bisegmentectomy group. Patients with T2 or T3 gallbladder cancer on preoperative CT exam or patients who …

  • 32 views
  • 21 Jan, 2021
  • 1 location
Perioperative Therapy Preoperative Chemotherapy Versus Chemoradiotherapy in Locally Advanced Gall Bladder Cancers

Locally advanced Gall bladders cancers not amenable for curative resection are often treated with chemotherapy alone which is the current standard of care. Randomized trials have shown survival benefit with combination chemotherapy in gallbladder cancers. Gallbladder cancer is not common western world and thus there is lack of evidence regarding …

laparoscopy
metastasis
adenocarcinoma
gemcitabine/cisplatin
combination chemotherapy
  • 38 views
  • 22 Jan, 2021
  • 1 location