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Found 199 clinical trials
Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC)

CTLA-4 Inhibitor Tremelimumab in patients with intrahepatic Biliary Tract Cancer

cancer
biliary tract cancer
hormone therapy
hepatitis b surface antigen
kidney function tests
  • 1 views
  • 04 Mar, 2021
  • 1 location
Phase II Study of Sitravatinib in Combination With Tislelizumab in Patients With Advanced Biliary Tract Cancer

This is open-label, phase II study enrolling advanced BTC patients who have failed to 1st-line chemotherapy.

  • 0 views
  • 03 Feb, 2021
  • 1 location
Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

This phase II trial studies how well olaparib works in treating patients with biliary tract cancer that has spread to other places in the body (metastatic) and with aberrant DNA repair gene

metastatic biliary tract cancer
hysterectomy
blood transfusion
oophorectomy
anticoagulants
  • 0 views
  • 15 Mar, 2021
  • 4 locations
Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers

The investigators design a phase II clinical study to explore the efficacy and safety of toripalimab plus lenvatinib as a second-line treatment in patients with advanced biliary tract cancers

  • 0 views
  • 26 Jan, 2021
  • 1 location
Immune Checkpoint Inhibition in Combination With Radiation Therapy in Pancreatic Cancer or Biliary Tract Cancer Patients

This is a prospective, randomized, open-label phase 2 study in patients with metastatic PC or BTC refractory or intolerant to at least one line of prior systemic chemotherapy with gemcitabine or platinum-containing regimens to determine the efficacy and safety of nivolumab or nivolumab plus ipilimumab administered concurrently with high dose …

systemic chemotherapy
neutrophil count
nivolumab
liver metastasis
metastasis
  • 0 views
  • 22 Feb, 2021
  • 1 location
Ramucirumab in Treating Patients With Advanced or Metastatic Previously Treated Biliary Cancers That Cannot Be Removed by Surgery

This phase II trial studies how well ramucirumab works in treating patients with previously treated biliary cancers that have spread to other places in the body and usually cannot be cured or

neutrophil count
gallbladder cancer
metastatic cholangiocarcinoma
heparin
warfarin
  • 0 views
  • 25 Jan, 2021
  • 1 location
Adjuvant Capecitabine vs Gemcitabine Plus Cisplatin in Resected Extrahepatic Cholangiocarcinoma

There is no proven adjuvant treatment after curative surgical resection in patients with cholangiocarcinoma, although previous meta-analysis suggested potential survival benefit of adjuvant chemotherapy or radiotherapy in patients with lymph node-positive resected cholangiocarcinoma. Despite of lack of level 1 evidence and no data which regimen is optimal, adjuvant chemotherapy is …

cholangiocarcinoma
carcinoma
adjuvant chemotherapy
cancer
extrahepatic cholangiocarcinoma
  • 15 views
  • 24 Jan, 2021
  • 1 location
Study of Pembrolizumab Following TACE in Primary Liver Carcinoma

Open label, single arm, multi-centre study of pembrolizumab following trans-arterial chemoembolization (TACE). Twenty-six to 32 evaluable participants with primary liver cancer (hepatocellular cancer; HCC) will be assessed. The primary objective is to determine the safety and tolerability of pembrolizumab following TACE. The secondary objective is to evaluate the efficacy of …

  • 0 views
  • 22 Feb, 2021
  • 1 location
Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors Pancreatic Cancer or Biliary Cancer

stopping them from dividing, or by stopping them from spreading. Giving afatinib dimaleate together with capecitabine may be a better treatment for solid tumors, pancreatic cancer, or biliary cancer.

neutrophil count
hysterectomy
gefitinib
capecitabine
solid tumour
  • 5 views
  • 28 Mar, 2021
  • 2 locations
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

This phase III trial studies how well gemcitabine hydrochloride and cisplatin given with or without nab-paclitaxel work in treating patients with newly diagnosed biliary tract cancers that have

  • 232 views
  • 27 Jan, 2021
  • 718 locations