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Found 214 clinical trials
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

trastuzumab
major surgery
brain metastasis
afatinib
tubal ligation
  • 6575 views
  • 08 Aug, 2022
  • 909 locations
XmAb20717 in Advanced Biliary Tract Cancers

This is a single-arm, phase II clinical trial to evaluate the efficacy of XmAb20717 in patients with advanced biliary tract cancers who have progressed on, or were intolerant of, a gemcitabine

  • 0 views
  • 24 Apr, 2022
  • 1 location
Molecular Profiling of Advanced Biliary Tract Cancers (COMPASS-B-MUHC)

Biliary tract cancer (BTC) accounts for <1% of all cancers, but remains a highly fatal malignancy. Surgical resection is the only hope for cure, but most patients present with advanced

measurable disease
biliary tract cancer
advanced biliary tract carcinoma
biliary cancer
palliative care
  • 0 views
  • 03 Mar, 2022
  • 1 location
Gemcitabine+ Capecitabine Vs Capecitabine in Curatively Resected Biliary Tract Cancer

resectable biliary tract cancer according to imaging studies after surgery. All the patients must complete a consent forms before participating in the clinical trial, and the estimated enrollment period is

  • 0 views
  • 29 Jun, 2022
  • 1 location
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers

Lymphocytes (TIL) and high-dose aldesleukin in patients with locally advanced, recurrent, or metastatic biliary tract cancer. These are low-incidence cancers carry a poor prognosis. Participants will include

metastasis
hepatitis b antigen
systemic therapy
platelet count
cancer
  • 31 views
  • 10 Aug, 2022
  • 1 location
A Study of HA121-28 Tablets in Advanced Biliary Tract Cancer

This study is a multicenter, open-label, single-arm phase II study to evaluate efficacy, safety, and pharmacokinetics characteristics of HA121-28 tablets in advanced biliary tract cancer (BTC

  • 0 views
  • 01 Jul, 2021
  • 2 locations
TST001 in Patients With CLDN18.2 Positive Previously Treated Advanced Biliary Tract Cancer

patients with CLDN18.2 positive previously treated unresectable advanced or metastatic Biliary Tract Cancer.

  • 0 views
  • 17 Jun, 2022
  • 1 location
Neoadjuvant Gemcitabine Plus Cisplatin With or Without Durvalumab in Resectable Biliary Tract Cancer

Considering that the poor prognosis of resected biliary tract cancer and negative impact on the survival outcomes of R1/R2 resection, neoadjuvant chemotherapy may improve R0 resection rates and

durvalumab
cholangiocarcinoma
metastasis
pet scan
malignant disease
  • 1 views
  • 02 Aug, 2021
  • 1 location
Trial of Infusional FOLFIRINOX in First Line Treatment of Advanced Biliary Tract Cancers (FBI-TRAC)

tract cancers and also to assess progression free survival and overall survival of FOLFIRINOX in first line treatment of advanced biliary tract cancers

fluorouracil
measurable disease
irinotecan
renal function
biliary cancer
  • 5 views
  • 25 Feb, 2022
  • 1 location
Phase Ib/II Single-arm Study of mFOLFOX6 Bevacizumab and Atezolizumab in Advanced Biliary Tract Cancer

The main objective of the study is to establish if patients with advanced bile duct cancer, who have already received a line of treatment for their disease, will receive any associated benefits from the combination of mFOLFOX6, bevacizumab and atezolizumab as a second-line therapy All patients who meet the criteria …

  • 0 views
  • 25 Nov, 2021
  • 2 locations