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Found 200 clinical trials
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

primary brain tumors
glioblastoma multiforme
solid tumors
bone marrow procedure
  • 19 Jan, 2022
  • 1030 locations
AZD6738 Plus Durvalumab in Biliary Tract Cancer

This trial will enroll advanced biliary tract cancer patients who have been previously treated with immunotherapy in either the 2nd or 3rd line. Patients will be treated with AZD6738 and

neutrophil count
follicle stimulating hormone
measurable disease
serum bilirubin
intrahepatic bile duct carcinoma
  • 30 Sep, 2021
  • 1 location
Molecular Profiling of Advanced Biliary Tract Cancers

Biliary tract cancer (BTC) accounts for <1% of all cancers, but remains a highly fatal malignancy. Surgical resection is the only hope for cure, but most patients present with advanced

palliative care
advanced biliary tract carcinoma
measurable disease
biliary cancer
  • 13 Aug, 2021
  • 1 location
Neoadjuvant Bintrafusp Alfa in Patients With Resectable Biliary Tract Cancer

The NEOBIL study aims to investigate the feasibility, safety and efficacy of neoadjuvant Bintrafusp alfa in patients with resectable biliary tract cancer.

neutrophil count
platelet count
pet scan
  • 23 Sep, 2021
  • 2 locations
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers

Lymphocytes (TIL) and high-dose aldesleukin in patients with locally advanced, recurrent, or metastatic biliary tract cancer. These are low-incidence cancers carry a poor prognosis. Participants will include

neutrophil count
hepatitis b antigen
extrahepatic cholangiocarcinoma
absolute neutrophil count
systemic therapy
  • 12 Feb, 2021
  • 1 location
NAPOLI-2: Fluorouracil Leucovorin and Nanoliposomal Irinotecan in Biliary Cancer

This is a study to evaluate the clinical activity of the combination of fluorouracil, leucovorin, and nanoliposomal irinotecan as second-line treatment in patients with advanced biliary tract

  • 10 Nov, 2021
  • 3 locations
Adjuvant Chemotherapy for Biliary Tract Cancer After Curative Resection

patients with biliary tract cancer (BTC) after curative resection.

  • 22 Jan, 2021
  • 1 location
Trial of Infusional FOLFIRINOX in First Line Treatment of Advanced Biliary Tract Cancers

tract cancers and also to assess progression free survival and overall survival of FOLFIRINOX in first line treatment of advanced biliary tract cancers

platelet count
measurable disease
biliary cancer
renal function
  • 06 Sep, 2021
  • 1 location
A Study of HA121-28 Tablets in Advanced Biliary Tract Cancer

This study is a multicenter, open-label, single-arm phase II study to evaluate efficacy, safety, and pharmacokinetics characteristics of HA121-28 tablets in advanced biliary tract cancer (BTC

  • 01 Jul, 2021
  • 2 locations
A Safety and Efficacy Study of Surufatinib Combination With Toripalimab in Patients With Recurrent Biliary Tract Cancer

A Phase Ⅱ, open-label, single-arm study to assess the safety, tolerability, and efficacy of Surufatinib Combination With Toripalimab in Patients With Recurrent Biliary Tract Cancer.

  • 06 Jan, 2022
  • 1 location