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Found 214 clinical trials
CIRcular and Non-coding RNAs as Clinically USeful Biomarkers in Pancreaticobiliary Cancers

Define the circRNA expression profile in PDAC and identify dysregulated circRNA candidates. These will be validated in further tissue samples. Evaluate candidate circRNA Expression in blood (plasma samples) as a clinically relevant diagnostic biomarker; expanding on the primary objective to include other diagnostic features such as specificity, area under the …

  • 0 views
  • 14 Mar, 2021
  • 1 location
A Study of Radiation Toxicity in the Liver Using MRI-Based Perfusion

Researchers at the the University of Michigan are conducting a research project to assess how a course of radiation therapy changes the way blood flows through the liver. To be able to do this, the researchers will be using MRI (magnetic resonance imaging) scans completed before, during, and after radiation …

  • 8 views
  • 26 Dec, 2021
  • 1 location
Identification of New Serum Diagnostic Markers of Hepatocellular Carcinoma

The purpose of this study is to identify blood markers that have the ability to diagnose liver cancer with improved accuracy, so that it can be used alone or in conjunction with alpha-feto protein (AFP)

hepatocellular carcinoma
hyperplasia
cirrhosis
carcinoma
  • 18 views
  • 23 Mar, 2022
  • 1 location
Viscoelasticity Imaging to Assess Liver Cancer (VisCan)

Ultrasound (US) used for hepatocellular carcinoma (HCC) surveillance suffers from low sensitivity (60-78%) due to fatty liver, obesity, and diffusely nodular appearance in cirrhosis. Once a suspicious malignant lesion is detected at US, guidelines recommend contrast-enhanced US, magnetic resonance imaging (MRI) or computed tomography (CT) scans to confirm suspicion. The …

  • 0 views
  • 21 Apr, 2022
  • 1 location
Registry to Collect Health Information Related to Fibrolamellar Cancer

The purpose of this study is to collect information about people with fibrolamellar cancer (FLC). This study is a registry of people with FLC around the world. This study will involve collecting information about participants, their medical history and the regular medical care they receive for FLC. The study will …

  • 0 views
  • 03 Dec, 2021
  • 1 location
A Study of Capecitabine Versus S-1 as Adjuvant Therapy in Patients With Biliary Tract Carcinoma After Surgical Resection

The purpose of this study is to assess the difference of safety and efficacy about Capecitabine and S-1 for treatment of patients with low-risk of recurrence after BTC surgery.

  • 0 views
  • 02 May, 2021
  • 1 location
Precision Medicine for Liver Tumours With Quantitative Magnetic Resonance Imaging and Whole Genome Sequencing

This will be a prospective, observational, cohort study to determine the impact of integrated diagnostics using quantitative magnetic resonance imaging, whole genome sequencing and digital pathology on intended patient management for liver cancer patients referred for liver resection. Participants with primary or secondary liver cancer will be recruited from Hampshire …

  • 0 views
  • 16 May, 2021
  • 1 location
National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

Background Primary Liver Cancer is the second most common cause of cancer-related death worldwide. It is the cancer with the fastest rising incidence and mortality in the United States. Researchers want to learn more about liver cancer to help them design better treatments. Objective To better understand liver cancer. Eligibility …

cancer
  • 0 views
  • 12 May, 2022
  • 7 locations
Hepatobiliary Tumors Tissue Samples Acquisition

Hepatobiliary tumors have a poor prognosis and high individual heterogeneity, so it is of great significance to find important prognostic markers and then screen out specific subgroups of people; meanwhile, chronic hepatitis, cirrhosis, and healthy control participants also need to show the evolution of tumors and discover specific diagnostic markers …

  • 0 views
  • 27 Jan, 2021
  • 1 location
A Prospective Study of UCAD for Diagnosing Benign or Malignant Biliary Obstruction and Follow-up

of patients with malignant biliary obstruction, including biliary tract cancer (BTC), pancreatic head carcinoma. CIN can be assessed using experimental techniques such as bulk DNA sequencing

cancer
endoscopic retrograde cholangiopancreatography
metastasis
carcinoma
biliary obstruction
  • 0 views
  • 15 May, 2022
  • 1 location