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Found 33 clinical trials
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

This is a study to collect the outcomes of stem cell transplantation for patients with hematologic diseases other than cancer.

anemia
sickle cell anemia
diamond-blackfan anemia
cancer
ejection fraction
  • 231 views
  • 22 Apr, 2022
  • 1 location
Genetic Variants Affecting the Clinical Severity of Beta Thalassemia

-thalassemia is one of the most common single gene disorder in Southern China. The phenotypic severity of beta thalassemia widely varies from mild to severe forms. Patients with the same beta

beta thalassemia
  • 0 views
  • 20 Jun, 2021
  • 1 location
Association of Hb F Level With Clinical Severity of Beta Thalassemia

The production of Hb F after birth is an important factor in modifying the clinical severity of beta thalassemia because an increased gamma-globin level will bind the additional a-globin and

beta thalassemia
  • 0 views
  • 20 Jun, 2021
  • 1 location
Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram

Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of

beta thalassemia
iron
  • 0 views
  • 26 Jun, 2021
  • 1 location
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research. We make it easy for patients to contribute to research for medical conditions that matter most to them, regardless of their location or ability to travel.

Accepts healthy volunteers
  • 293 views
  • 26 Jan, 2022
  • 1 location
STUDY INCIDENCE AND CHARACTERISTICS OF MALIGNANT NEOPLASIES IN PATIENTS WITH HEMOGLOBINOPATHY FOLLOWED IN ITALY (Tum001)

The Trial aims to increase the information available on the relevance of tumor pathology in hemoglobinopathies, updating the data relating to hepatocarcinoma and investigating which other tumors are more frequent in patients with hemoglobinopathies. Still, in relation to tumor pathology, the study will evaluate any differences between the different types …

  • 0 views
  • 26 Apr, 2022
  • 1 location
Atrial Fibrillation in Beta-Thalassemia

The study aims to evaluate the clinical, laboratory and instrumental differences that exist between beta-thalassemia patients with atrial fibrillation and those not affected by arrhythmia.

electrocardiogram
fibrillation
arrhythmia
  • 0 views
  • 07 Oct, 2022
  • 1 location
Observing the Changes of Endocrine and Metabolism in Patients With Thalassemia Major

Patient with thalassemia major have many endocrine diseases, such as hypopituitarism, hypothyroidism, hypoparathyroidis, osteoporosis, and etc.. These problems may be due to anemia itself or

anemia
iron
osteoporosis
  • 1 views
  • 07 Feb, 2022
  • 1 location
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia

This study aims to: Assess the cognitive function in children with beta thalassemia Evaluate the fatigue in beta thalassemic children Assess the health related

beta thalassemia
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
An Observational Long-term Safety and Efficacy Follow-up Study After Ex-vivo Gene Therapy With BIVV003 in Severe Sickle Cell Disease (SCD) and ST-400 in Transfusion-dependent Beta-thalassemia (TDT) With Autologous Hematopoietic Stem Cell Transplant

Primary Objectives: Long-term safety of BIVV003 in participants with severe sickle cell disease (SCD) and ST- 400 in participants with transfusion-dependent beta-thalassemia (TDT)

  • 0 views
  • 04 Oct, 2022
  • 1 location