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Found 73 clinical trials
Interest of Auriculotherapy in the Management of Chronic Insomnia (AURICULO-DODO)

The aim of the study is to show that auriculotherapy is effective in the treatment of chronic insomnia.

chronic insomnia
  • 25 Mar, 2022
  • 2 locations
Non-invasive Ventilation and Dex in Critically Ill Adults (inDEX)

Non-Invasive ventilation (NIV) is a life saving intervention for patients with acute respiratory failure (ARF). Some patients are not able to tolerate the NIV intervention and ultimately fail, requiring the use of invasive mechanical ventilation (IMV) and intubation. Sedation may improve a patient's NIV tolerance. However, this practice has not …

non-invasive ventilation
assisted ventilation
acute respiratory failure
  • 27 May, 2022
  • 1 location
Regional Midazolam in Quadratus Lumborum Block

Midazolam has been used in regional anesthesia of brachial plexus block; it has offered accepted postoperative pain relief. This study will use it in as an adjuvant to bupivacaine 0.25% in quadratus lumborum block in caesarean section

postoperative pain
pain relief
  • 04 Oct, 2022
  • 1 location
DexmedetOmidine Complement Treats Chronic insOmnia and Improves Circadian Rhythm (DOCTOR) (DOCTOR)

It has been reported that dexmedetomidine, alpha-2 adrenoceptor agonist, can activate endogenous neural sleep pathways in the central nervous system. This randomised, double-blinded and controlled trial was designed to investigate whether dexmedetomidine can improve/treat chronic insomnia patients. Its effects on sleep quality and improvement, EEG and circadian rhythm, brain connectivity, …

chronic insomnia
body mass index
  • 13 Apr, 2022
  • 1 location
Decreasing Patient Anxiety During Revascularization of Chronic Total Coronary Occlusions Using Virtual Reality Glasses. (ReViCTO)

Percutaneous coronary angioplasty on chronic total occlusions is a complex procedure. The possibility of performing these procedures without anesthesia and sedation avoids the risks associated with anesthesia and sedation, but, on the contrary, subjects the patient to pain and anxiety during the procedure. Virtual reality (VR) has been successfully used …

  • 04 Oct, 2022
  • 1 location
Impact of Cardiac Coherence on Anxiety in Patients Operated on for a Peritoneal Carcinosis (COCOON)

The investigator proposes to use the cardiac coherence technique to diminish anxiety before the surgery of a peritoneal carcinosis of colon or stomach or ovary and pseudomyxoma or peritoneal mesothelioma.

  • 22 Mar, 2022
  • 1 location
Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients

Delirium is common in septic patients, especially those receiving mechanical ventilation in the intensive care unit (ICU). Dexmedetomidine is a highly selective α2 adrenoreceptor agonist with anxiolytic, sedative, analgesic, and anti-inflammatory effects. Use of dexmedetomidine in mechanically ventilated ICU patients is associated with less delirium and improved outcomes. However, dexmedetomidine …

organ failure
mechanical ventilation
  • 03 May, 2022
  • 1 location
Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder

The majority of opioid users meet criteria for anxiety and depressive disorders, but most substance use disorder treatment programs do not offer treatment for co-occurring mental health problems. Anxiety and depression may also be directly linked to opioid use itself. Although treatments have been developed for anxiety and depressive symptoms …

behavioral therapy
depressive disorder
substance use
  • 22 Oct, 2021
  • 1 location
Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease

This is a randomized, double-blinded, placebo-controlled, crossover trial that aims to 1) determine the efficacy of THC-free cannabidiol (CBD oil) in reducing the severity of agitation among participants and 2) determine whether THC-free CBD oil can reduce the burden on caregivers and increase the participants' quality of life.

alzheimer's disease
mini-mental state examination
mental state examination
  • 14 May, 2022
  • 1 location
Interest of tDCS in Help for Supporting Alcohol Abstinence (ITAMAA)

The aim of the study is to evaluate in patients with alcohol disorder and forehand weaned the efficiency of 10 active tDCS sessions versus 10 sham (placebo) sessions in the support of abstinence at 3 months.

  • 05 May, 2022
  • 1 location