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Found 73 clinical trials
Whole Coffee Cherry Study

There has been increasing interest in natural dietary supplements that may support healthy cognition. Recent studies have demonstrated promising effects of bioactive phytochemicals (e.g., polyphenols) on cardiovascular and endocrine health outcomes. As such, an increasingly intriguing line of inquiry is whether materials high in these compounds may also have effects …

Accepts healthy volunteers
  • 0 views
  • 06 Oct, 2021
  • 1 location
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane

The purpose of this protocol is to determine the effect of two clinically applicable Dexmedetomidine dosages (0.5mcg/kg and 1mcg/kg) on the minimum alveolar concentration (MAC) of Sevoflurane in children between the age ranges of: 1-6 months; 6-12 months of age and 12 months-36 months years of age.

Accepts healthy volunteers
  • 8 views
  • 27 Apr, 2022
  • 1 location
Can Connected Devices Increase the Success Rate of Benzodiazepine Withdrawals in the Elderly?

This is a prospective randomized open study, which aims to evaluate the benefit of a connected watch to help people aged 65 years and older to withdraw from BZD over a six-month period, compared with classical withdrawal (e.g without connected watch). The study will include 100 patients, 50 in the …

  • 0 views
  • 03 Nov, 2021
  • 1 location
Opioid vs. Benzodiazepine-based Sedation for Mechanically Ventilated Patients in the Internal Medicine Ward

Opioid-based sedation as a first line in mechanically ventilated patients has been considered the "gold standard" in intensive care unit patients around the world for several decades. Advantages of opiate-based sedation, compared to benzodiazepine-based sedation, which has been used in the past, include a reduction in delirium scores, better pain …

  • 0 views
  • 05 May, 2022
  • 1 location
Music Therapy in Procedural Sedation in the Emergency Department

The investigators propose to determine whether listening to classical music during a sedation procedure decreases the need for procedural sedation medication. It is a two arm study comparing music vs no music by headphones so that the investigator is blinded to the intervention. The outcome variable is amount of sedative …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Percutaneous Neurostimulation for Treatment of Paroxysmal Sympathetic Hyperactivity in Children With Acute Severe Brain Injury

Survivors of severe brain injury, such as lack of oxygen or severe traumatic brain injury, frequently experience Paroxysmal Sympathetic Hyperactivity (PSH). PSH is characterized by disabling symptoms such as a fast heart rate, high blood pressure, rapid breathing, rigidity, tremors, and sweating due to uncontrolled sympathetic hyperactivity in the nervous …

  • 0 views
  • 14 Oct, 2022
  • 1 location
De-adopting Routine Preoperative Benzodiazepines for Older Surgical Patients (DROP-Benzo)

Over 21 million surgical procedures take place among adults aged 65 and older in the US each year, and most older surgical patients in the US now receive benzodiazepines (e.g., midazolam

  • 0 views
  • 07 Oct, 2022
  • 1 location
Impact of Remimazolam on Prognosis After Bladder Cancer Surgery

after TURBT are at risk for recurrence and progression. Benzodiazepines are proved to inhibit proliferation of multiple types of cancer cells in vitro. Delirium is an acute onset and transient cerebral

transurethral bladder excision
transurethral resection
invasive bladder cancer
surgery for bladder cancer
bladder tumor
  • 1 views
  • 19 Jul, 2021
  • 6 locations
Sleep Disturbances and Delirium (SLEEP)

minimized by multimodal interventions (pain management, shortening the duration of mechanical ventilation, light sedation, avoiding benzodiazepines, routine delirium monitoring, and early mobilization

benzodiazepines
sleep disturbances
  • 0 views
  • 15 Jun, 2022
  • 1 location
Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium (B-Free)

B-FREE is a pragmatic, multicentre, cluster crossover trial evaluating whether a policy limiting the use of intra-operative benzodiazepine reduces post-operative delirium when compared with a policy of 'ad libitum' administration. The knowledge generated by this study will provide the basis for cardiac anesthesia practice guidelines.

heart surgery
benzodiazepines
confusion
anesthesia
postoperative delirium
  • 10 views
  • 28 Oct, 2022
  • 1 location