benralizumab Clinical Research Trials

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Severe Uncontrolled Asthma

1092 views
08 Nov, 2020
1 location

A Study of Benralizumab in Patients With Eosinophilic Esophagitis

The aim of this Phase 3 study is to investigate the use of benralizumab as a treatment for patients with EoE. The effect of doses of benralizumab on EoE histologic signs and symptoms will be

0 views
17 Feb, 2021
73 locations

Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.

This is a randomized, double blind, active-controlled, parallel group, multicenter 52-week Phase 3 study to compare the efficacy and safety of benralizumab 30 mg versus mepolizumab 300 mg

nasal abnormality

eosinophilia

corticosteroid therapy

cyclophosphamide

oral prednisolone

20 views
15 Feb, 2021
75 locations

A Phase 3 Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)

This is a multicentre, randomised, double-blind (DB), parallel-group, placebo-controlled, 24-week Phase 3 study to compare the efficacy and safety of benralizumab versus placebo administered by

0 views
13 Feb, 2021
42 locations

Effect of Benralizumab in Patients With Severe Nasal Polyps

This is a randomized placebo controlled trial to evaluate the effect of benralizumab on people with severe nasal polyps.

3 views
08 Nov, 2020
1 location

Benralizumab in Patients With Inadequate Response to Anti-IL5 Monoclonal Antibody Therapies

In severe prednisone-dependent eosinophilic asthma, Benralizumab would suppress airway eosinophilia that is not suppressed by either Mepolizumab or Reslizumab and this would be associated with

22 views
28 Jan, 2021
1 location

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma

This study will evaluate the PK, PD and long-term safety of Benralizumab administered subcutaneously in 30 children aged 6 to 11 years with severe eosinophilic asthma. Up to an additional 3

1 views
25 Feb, 2021
18 locations

Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics

The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics. Changes will be assessed over 48 week treatment

airway remodelling

benralizumab

fluticasone

corticosteroids

pulmonary function test

119 views
17 Feb, 2021
46 locations

Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID)

This is a randomized, double-blind, placebo-controlled, parallel-group, international, multicenter, Phase 3 study to evaluate the efficacy and safety of repeat dosing of benralizumab 30 mg

rhinosinusitis

corticosteroids

polyposis

aspirin

eosinophil count

20 views
24 Jan, 2021
35 locations

Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis

The purpose of the study is to compare the efficacy and safety of benralizumab versus placebo and to compare benralizumab dosing regimens during extension period.

0 views
18 Feb, 2021
44 locations

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Found 30 clinical trials