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Found 18 clinical trials
Featured trial
Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

  • 940 views
  • 25 Mar, 2021
  • 12 locations
None
Belimumab Treatment for IgG4-related Disease

during the treatment. Belimumab is an IgG1-lambda monoclonal antibody that prevents the survival of B lymphocytes by blocking the binding of soluble human B lymphocyte stimulator protein (BLyS) to

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)

infections. Low levels of CD4 cells may make a person more likely to get sick. There are no approved treatments for ICL. Researchers think a drug called belimumab may be able to help in specific situations

  • 109 views
  • 01 Sep, 2021
  • 1 location
None
Synergetic B-cell Immunomodulation in SLE - 2nd Study.

-cell targeting by starting treatment with belimumab (anti-BAFF) followed by rituximab(anti-CD20) in lupus nephritis patients.

immunosuppressive agents
vasculitis
pericarditis
myositis
mycophenolate
  • 18 views
  • 07 Mar, 2021
  • 4 locations
None
Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)

The purpose of this study is to evaluate the pharmacokinetics (PK), safety, and pharmacodynamics (PD) of repeat doses of 200 milligrams per milliliter (mg/mL) belimumab administered via SC

chloroquine
antimalarials
nsaids
prednisone
mycophenolate
  • 2 views
  • 18 Oct, 2021
  • 13 locations
None
Belimumab With Rituximab for Primary Membranous Nephropathy

The primary objective of this study is to evaluate the effectiveness of belimumab and intravenous rituximab co-administration at inducing a complete remission (CR) compared to rituximab alone in

mammogram
remission
systemic lupus erythematosus
cancer
kidney biopsy
  • 296 views
  • 12 Sep, 2021
  • 11 locations
None
Trial of Belimumab in Early Lupus

This two year study will evaluate the effects of giving belimumab (Benlysta) to patients with Early Lupus. Early lupus is a diagnosis of lupus within 2 years. Subjects will be randomized to

benlysta
hydroxychloroquine
belimumab
corticosteroids
ds dna
  • 0 views
  • 12 Dec, 2021
  • 1 location
None
The BeLimumab Antiphospholipid Syndrome Trial (BLAST)

AIM: The primary objective of the BeLimumab Antiphospholipid Syndrome Trial (BLAST) is to evaluate the safety and tolerability of belimumab for up to 24 months in patients with persistent aPL

heparin
haemostasis
lupus
glycoprotein
warfarin
  • 6 views
  • 16 Oct, 2021
  • 1 location
None
Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies

This is intended to be an initial "proof-of-concept" study to show feasibility, validate assays and approaches, and explore dosing and safety of belimumab in pulmonary emphysema patients who

pulmonary disease
ct scan
emphysema
COPD
cotinine
  • 171 views
  • 10 Nov, 2021
  • 1 location
None
Rituximab and Belimumab Combination Therapy in PR3 Vasculitis

Mechanistic study to assess whether dual B-cell immunotherapy by co-administration of rituximab and belimumab will result in improvements in biological endpoints, functional outcomes and

prednisolone
vasculitis
belimumab
anti-neutrophil cytoplasmic antibody
microscopic polyangiitis
  • 19 views
  • 25 Jan, 2021
  • 1 location