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Found 101 clinical trials
Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

This early phase I trial studies the side effects of autologous dendritic cells and a vaccine called Prevnar in treating patients with liver cancer that cannot be removed by surgery after undergoing standard high-dose external beam radiotherapy. Autologous dendritic cells are immune cells generated from patients' own white blood cells …

international normalized ratio
pneumococcal 13-valent conjugate vaccine
tumor cells
cancer
white blood cells
  • 6 views
  • 14 Jun, 2022
  • 1 location
Assessing the Rate of Complications in X-Ray Therapy Versus Proton Beam Radiation Therapy After Breast Conserving Surgery or Mastectomy in Treating Patients With Breast Cancer

This phase II trial investigates the rate of complications of x-ray therapy versus proton beam radiation therapy after breast conserving surgery or mastectomy in treating patients with breast

proton beam radiation therapy
mastectomy
tumor cells
cancer
  • 5 views
  • 17 Jun, 2022
  • 3 locations
Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

grade II or III glioma. Proton beam radiation therapy uses tiny charged particles to deliver radiation directly to the tumor and may cause less damage to normal tissue. Intensity-modulated or photon

x-rays
MRI
blood transfusion
oligoastrocytoma
neutrophil count
  • 72 views
  • 25 May, 2022
  • 14 locations
Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT)

To investigate a potential toxicity benefit of preoperative radiation therapy with protons compared to conventional photon beam radiation therapy in patients with locally advanced rectal cancer

  • 0 views
  • 14 May, 2021
  • 1 location
IMRT Followed by Pembrolizumab in the Adjuvant Setting in Anaplastic Cancer of the Thyroid (IMPAACT): Phase II Trial Adjuvant Pembrolizumab After IMRT in ATC

This is an open label, single center, phase 2 trial of adjuvant pembrolizumab after external beam radiation to the primary tumor in patients with stage IVB (disease localized to the neck) ATC

  • 0 views
  • 22 Jul, 2022
  • 1 location
Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer

Hypo-Combi Trial: A Prospective Phase I/II Study of Combined Hypofractionated External Beam Radiation Therapy (EBRT) plus Interstitial High-Dose-Rate Brachytherapy (HDR-BT) for Intermediate/High

  • 0 views
  • 23 Aug, 2021
  • 1 location
Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic Cancer (PARC)

This is an interventional, single arm, open-label, feasibility trial with gemcitabine and nab-paclitaxel, followed by concomitant proton therapy and capecitabine, followed by re-evaluation and surgery (when feasible) for patients with borderline resectable pancreatic cancer.

capecitabine
neutrophil count
resectable pancreatic cancer
paclitaxel
chemoradiotherapy
  • 0 views
  • 15 Sep, 2022
  • 2 locations
Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

This trial studies how well proton beam radiation therapy compared with intensity modulated photon radiotherapy works in treating patients with stage I-IVA esophageal cancer. Proton beam

  • 15 views
  • 24 Apr, 2022
  • 36 locations
SBRT + Atezolizumab + Bevacizumab in Resectable HCC

. This study involves the following study interventions: Atezolizumab Bevacizumab Stereotactic Beam Radiation Therapy (SBRT) Surgery

ct scan
neutrophil count
measurable disease
  • 0 views
  • 23 Mar, 2022
  • 1 location
A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer

The purpose of this study is to find out whether combining a shorter than standard course of ADT with standard prostate brachytherapy and hypofractionated external beam radiation therapy is a

  • 0 views
  • 25 Jul, 2022
  • 7 locations