Found 7 clinical trials
Synergetic B-cell Immunomodulation in SLE - 2nd Study. (SynBioSe-2)
-cell targeting by starting treatment with belimumab (anti-BAFF) followed by rituximab(anti-CD20) in lupus nephritis patients.
- 28 views
- 27 Apr, 2022
- 4 locations
Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)
Background People with Idiopathic CD4 lymphopenia (ICL) have lower numbers of a type of white blood cell called CD4 cells. White blood cells fight against infections. Low levels of CD4 cells may make a person more likely to get sick. There are no approved treatments for ICL. Researchers think a …
- 109 views
- 10 Apr, 2023
- 1 location
Belimumab in Patients With Chronic Lymphocytic Leukemia (BeliVeR)
stimulator (BlyS, also called BAFF), which can be bound by belimumab, a human anti-BAFF antibody. Moreover, recombinant human (rh)BAFF can dose dependently reverse cytotoxic effects of venetoclax, which
- 0 views
- 25 Mar, 2022
First-line Antibiotic Therapy for Early-stage HP(+) Gastric Pure DLBCL
pure (de novo) DLBCL The durability of complete histological remission after antibiotics The usefulness of pattern of NF-kB, BCL10, BAFF, and CagA by IHC staining in prospectively
- 3 views
- 21 Jan, 2021
- 1 location
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, 2-Stage Trial to Evaluate Efficacy and Safety of Telitacicept Compared to Placebo in Patients With Moderately to Severely Active Systemic Lupus Erythematosus
The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of moderately to severely active SLE.
- 0 views
- 24 Oct, 2022
- 6 locations
CAR-T Cells Targeting Autoimmune Diseases
The purpose of this study is to assess the feasibility, safety and efficacy of CAR-T cell therapy in patients with autoimmune disease. Another goal of the study is to learn more about the safety and function of the CAR-T cells and their persistency in autoimmune disease patients.
- 0 views
- 04 Oct, 2022
- 2 locations
Biorepository and Registry for Plasma Exchange Patients
referred to DeGowin for plasma exchange. The immediate objective of the study is to examine antibody levels (IgG/IgM) and BAFF levels in the blood of these patients over the course of the plasma exchange
- 3 views
- 22 Aug, 2021
- 1 location