Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 92 clinical trials
Sphingosine-1-phosphate and Pneumonia (SOPN)

Pneumonia is a major infectious cause of death worldwide and imposes a considerable burden on healthcare resources. Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid and involved in many physiological processes including immune responses and endothelial barrier integrity. In term of endothelial barrier integrity, S1P plays a crucial role in protecting lungs …

community acquired pneumonia
  • 0 views
  • 11 Feb, 2022
  • 1 location
Omadacycline vs. Moxifloxacin for the Treatment of Community-Acquired Bacterial Pneumonia

The purpose of this study is to evaluate the safety and efficacy of omadacycline as compared to moxifloxacin in the treatment of adults with community-acquired bacterial pneumonia.

  • 0 views
  • 09 Jun, 2022
  • 18 locations
  • 45 views
  • 15 Oct, 2022
  • 17 locations
A Phase 2/3 Open-label, Randomized, Active-controlled Clinical Study to Evaluate the Safety, Tolerability, Efficacy and Pharmacokinetics of MK-7655A in Pediatric Participants From Birth to Less Than 18 Years of Age With Confirmed or Suspected Gram-negative Bacterial Infection

infection types: hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP); complicated intra-abdominal infection (cIAI); or complicated urinary tract infection (cUTI

  • 74 views
  • 17 Oct, 2022
  • 36 locations
Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer Lung Cancer Obesity Vaccine-Preventable Illness and LivER Cancer

The purpose of CLOVER is to utilize Epic Healthy Planet to increase adherence to United States Preventive Services Task Force (USPSTF) and Centers for Disease Control and Prevention (CDC) recommendations in adults age 50 and older.

vaccination
lung cancer screening
pneumonia
lung carcinoma
cancer
  • 0 views
  • 09 Dec, 2021
  • 1 location
Comparison of Procedural Yield of Bronchoalveolar Lavage Using Three Different Techniques in Subjects Undergoing Flexible Bronchoscopy (BAL-3T)

cytology and microbiology examination studies including AFB, MGIT, GeneXpert, Galactomannan, fungal cultures to diagnose various conditions like PAP, eosinophilic pneumonia, bacterial or fungal infections

  • 0 views
  • 10 Jul, 2022
  • 2 locations
Effectiveness of Oral Management Strategies on Improving Oral Frailty and Oral Bacteria

The aim of this study is to examine the effectiveness of nurse-driven oral management for improvements of oral frailty, and oral bacteria pneumonia patients with oral frailty using a randomized controlled trial (RCT) design. Hospitalized pneumonia patients (N = 90) will be randomized into three groups (oral management, oral care, …

  • 0 views
  • 19 Jun, 2022
  • 1 location
BL Infusion Trial: Beta-lactam Continuous Versus Intermittent Infusion and Associated Bacterial Resistance and Therapy Outcomes in Critically Ill Patients With Severe Pneumonia

The study plans to randomize a total of 240 patients infected with Gram-negative bacterial pneumonia to receive beta-lactam (meropenem, cefepime, or piperacillin/tazobactam) continuous or

chest radiograph
cough
fever
respiratory failure
beta-lactam
  • 0 views
  • 13 Mar, 2022
  • 1 location
Population Pharmacokinetics of Cefiderocol During Acute Pulmonary Exacerbations in Adult Patients With Cystic Fibrosis

There is established evidence that adult patients with Cystic Fibrosis (CF) may have altered antibiotic pharmacokinetics compared with non-CF patients. Cefiderocol is a newly approved broad spectrum intravenous siderophore cephalosporin antibiotic, which has potent in vitro activity against multidrug resistant Pseudomonas aeruginosa, Burkholderia cepacia complex, Achromobacter species, and Stenotrophomonas maltophilia, …

antibiotics
fibrosis
burkholderia cepacia
  • 0 views
  • 24 Oct, 2022
  • 3 locations
A Controlled Human Pneumococcal Infection Model (PIM) Study (PIM)

Infection with Streptococcus pneumoniae (the pneumococcus) is the leading cause of pneumonia, bacterial meningitis and bacteraemia worldwide in the very young and the elderly. Although

antibiotics
vaccination
meningitis
Accepts healthy volunteers
pneumonia
  • 0 views
  • 17 Jun, 2022
  • 1 location