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Found 63 clinical trials
Transcutaneous Carbon Dioxide Monitoring in Neonates Receiving Therapeutic Hypothermia for Neonatal Encephalopathy

The aim of our study is to evaluate the feasibility of applying transcutaneous CO2 monitoring (tcPCO2) in neonates receiving therapeutic hypothermia and to quantify the agreement between tcPCO2 and PCO2 in this population with or without respiratory support. Although, transcutaneous measurement of CO2 tension is the most commonly used non-invasive …

  • 21 Apr, 2022
Lifestyle Self-medication and Use of Nutraceuticals in a Population of Italian and Spanish Students

University students are considered a population class with a high risk of malnutrition and/or obesity, metabolic and cardiovascular diseases, with a tendency to misuse drugs and self-medication. The interest in a healthy diet can lead to a psychological obsession known as orthorexia, frequent among students in the biomedical field and …

  • 26 Jan, 2021
  • 3 locations
Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

infection, bacteraemia/sepsis, skin and soft tissue infection, endocarditis or other infections, each as far as covered by the respective nationally relevant SmPC.

infection, nosocomial
soft tissue infection
nosocomial infections
bacterial infections
bacterial meningitis
  • 27 Jan, 2022
  • 23 locations
The Efficacy and Safety of Daptomycin in the Treatment of Gram-positive Bacterial Infection.

This study aims to collect and analyze clinical data of daptomycin to explore the efficacy and safety of daptomycin in the treatment of Gram-positive bacterial infections. And optimize the dosing regimen based on these data.

  • 26 Jan, 2021
  • 1 location
Develop a Multi-disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Different screening modalities evaluation to develop algorithms to predict pregnancy complications in twin pregnancies, and evaluation of serologic response to BNT162b2 Pfeizer/BioNTech vaccination.

Accepts healthy volunteers
  • 20 Oct, 2021
  • 4 locations
Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia

This study aims to assess whether ertapenem as an empiric treatment of third-generation-cephalosporin resistant Enterobacteriaceae (3GCRE) bacteremia is non-inferior to other carbapenems in term

  • 02 May, 2022
  • 1 location
Effect of Vitamin B12 on the Development of Sepsis, in Culture Positive Patients (Vit B12)

This is an prospective observational study assessing the effect of vitamin B12 on the odds of developing sepsis in patients with infection confirmed by a positive culture result. The hypothesis is that patients with infection confirmed by positive cultures who develop sepsis have lower vitamin B12 levels than patients infection, …

  • 11 Feb, 2022
  • 1 location
Blood Markers for Identifying & Investigating Infection With COVID19 & Sepsis in Children.

with high fevers and inflammation. Sepsis, also called blood poisoning, is an abnormal response of the body to some infections. We aim to conduct research in children under 18 admitted to

acute illness
  • 02 Jun, 2021
  • 1 location
Function of Circulating Exosomes in Sepsis-induced Immunosuppression

This is a single-center prospective bio-specimen analysis and observational study aiming to define immune pathways disrupted in bacterial sepsis and to identify clinically useful biomarkers of immune status.

systemic inflammatory response syndrome
bacterial infection
inflammatory response
  • 04 Aug, 2021
  • 1 location
Study of the Ecological and Evolutionary Dynamics of Escherichia Coli in the Digestive Commensal Flora

infections, first cause of bacteremia. However, little is known about the dynamics of intestinal colonization of the human host. Understanding the dynamics of colonization is crucial because selection for

Accepts healthy volunteers
  • 15 Dec, 2021
  • 2 locations