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Found 63 clinical trials
Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia (diSArm)

Available Antibiotic Therapy Compared to Best Available Antibiotic Therapy Alone for the Treatment of Adults With Bacteremia Due to Staphylococcus aureus

staphylococcus
blood culture
antibiotic therapy
antibiotics
bacteremia
  • 0 views
  • 30 May, 2022
  • 3 locations
Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia

Gram negative bacteremia with a urinary tract source of infection (GNB). Five days after initiation of antimicrobial therapy for GNB, participants are randomized 1:1 to parallel treatment arms

  • 22 views
  • 26 Jan, 2021
  • 12 locations
ERAdicate S. Aureus in Patients With Bacteremia and Endocarditis (ERASE)

Staphylococcus aureus bacteremia (SAB), including left- and right-sided infective endocarditis (IE).

  • 0 views
  • 26 May, 2022
Rapid Blood Culture Identification Panel in Pediatric Patients in Guatemala

The purpose of this study is to assess the clinical impact of a rapid multiplex PCR blood culture identification panel on time to optimal antimicrobial therapy when compared to conventional microbiological culture methods in children hospitalized in a low resource setting in Guatemala City.

antimicrobial agent
antibiotics
blood culture
antimicrobials
  • 0 views
  • 03 May, 2022
  • 1 location
DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus Bacteremia

completion of therapy in patients with complicated bacteremia or right-sided native valve Infective Endocarditis (IE) caused by S. aureus who have cleared their baseline bacteremia. Approximately 200

  • 12 views
  • 17 Jun, 2022
  • 16 locations
Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

The purpose of this superiority study is to evaluate the efficacy and safety of exebacase in addition to standard of care antibiotics (SoCA) compared with SoCA alone for the treatment of patients with Staphylococcus aureus (S. aureus) bloodstream infections (BSI), including right-sided infective endocarditis (IE). Patients will be randomized to …

  • 36 views
  • 01 May, 2022
  • 58 locations
Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults

This is an open-label, randomized, multi-center, interventional, active-controlled Phase 4 study to evaluate the efficacy and safety of CAZ-AVI versus BAT in the treatment of infected participants with selected infection types (Hospital Acquired Pneumonia [HAP] (including Ventilator-Associated Pneumonia [VAP]); Complicated Urinary-Tract Infection [cUTI]; Complicated Intra-Abdominal Infection [cIAI]; Bloodstream Infection [BSI]) …

ceftazidime
meropenem
antibacterial
abdominal infection
bloodstream infection
  • 0 views
  • 28 Jun, 2022
  • 10 locations
Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia (CALIF)

CALIF study is a monocentric observational study which aim is to analyse the value of adding procalcitonin (PCT, a pre-hormon increased in bacterial infection and septicaemia) in the management of chemo-induced febrile neutropenia occurring in patient with solid tumour. Febrile neutropenia will be managed according to international guidelines. PCT will …

  • 10 views
  • 30 Jan, 2022
  • 1 location
Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE Infections

Enterobacteriaceae infections with IMI/REL including in bacteremia, and to analyze treatment outcomes in use of IMI/REL for KPC-producing infections compared to historical clinical outcome data with CZA and MVB use

carbapenem
cilastatin
imipenem
antibiotics
ceftazidime
  • 8 views
  • 14 May, 2022
  • 1 location
Effects of Resistant Starch Diet on the Gut Microbiome in Chronic Kidney Disease

these beneficial bacteria called butyrate. The investigators will also determine changes in the gut bacteria and products of the bacteria in the blood.

nephropathy
glomerular filtration rate
  • 0 views
  • 11 Feb, 2022
  • 1 location