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Found 61 clinical trials
Develop a Multi-disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Different screening modalities evaluation to develop algorithms to predict pregnancy complications in twin pregnancies, and evaluation of serologic response to BNT162b2 Pfeizer/BioNTech vaccination.

Accepts healthy volunteers
  • 0 views
  • 20 Oct, 2021
  • 4 locations
Cefepime vs. Carbapenems for Treating AmpC β-lactamase-producing Enterobacteriaceae Bloodstream Infections (CARBAPENEM)

Recent international recommendations suggest the use of carbapenem rather than cefepime in this situation, but with a low level of evidence, given the few existing studies. As cefepime is a less broad-spectrum antibiotic than carbapenems, its use would limit the selection of multidrug-resistant bacteria.

bacteremia
carbapenem
antibiotics
  • 0 views
  • 07 Oct, 2022
Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia

This study aims to assess whether ertapenem as an empiric treatment of third-generation-cephalosporin resistant Enterobacteriaceae (3GCRE) bacteremia is non-inferior to other carbapenems in term

bacteremia
carbapenem
cephalosporins
  • 30 views
  • 02 May, 2022
  • 1 location
Effect of Vitamin B12 on the Development of Sepsis, in Culture Positive Patients (Vit B12)

This is an prospective observational study assessing the effect of vitamin B12 on the odds of developing sepsis in patients with infection confirmed by a positive culture result. The hypothesis is that patients with infection confirmed by positive cultures who develop sepsis have lower vitamin B12 levels than patients infection, …

septicemia
  • 1 views
  • 11 Feb, 2022
  • 1 location
Predictors of Infective Endocarditis Among Patients Managed for Staphylococcus Aureus Bacteremia, Particularly Staphylococcus Aureus Bacteriuria, and Time to Blood Culture Positivity (BACT_URIE)

Staphylococcus aureus is a frequent cause of primary or secondary bacteremia. It is also responsible for many cases of infective endocarditis, for which the therapeutic management is specific

bacteremia
blood culture
staphylococcus
  • 0 views
  • 07 Oct, 2022
  • 1 location
Blood Markers for Identifying & Investigating Infection With COVID19 & Sepsis in Children.

with high fevers and inflammation. Sepsis, also called blood poisoning, is an abnormal response of the body to some infections. We aim to conduct research in children under 18 admitted to

acute illness
  • 0 views
  • 02 Jun, 2021
  • 1 location
Effects of Non-calorie Sweeteners Mono- and Disaccharides on Intestinal Barrier Function

The aim of the present study is to determine the effect of non-nutritive sweeteners on intestinal barrier function and inflammatory markers in healthy subjects in comparison to mono- and disaccharides.

  • 0 views
  • 19 Mar, 2021
  • 1 location
Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study (TIGRIS)

Prospective, multicenter, randomized, open-label study of standard of care plus the PMX cartridge versus standard of care alone in patients with endotoxemic septic shock

dopamine
vasopressor
resuscitation
oliguria
platelet count
  • 13 views
  • 07 Jul, 2022
  • 15 locations
Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components

This study will investigate the gut microbiota-mediated effects of whole wheat consumption on human health in adults with pre-diabetes. Participants will complete two phases of intervention in random order in which they will consume either whole wheat bread (4 servings) or white bread a day for two weeks prior to …

fasting blood glucose
diabetes
microbiota
fasting
  • 0 views
  • 11 May, 2022
  • 1 location
Study of the Ecological and Evolutionary Dynamics of Escherichia Coli in the Digestive Commensal Flora

infections, first cause of bacteremia. However, little is known about the dynamics of intestinal colonization of the human host. Understanding the dynamics of colonization is crucial because selection for

Accepts healthy volunteers
  • 0 views
  • 15 Dec, 2021
  • 2 locations