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Found 26 clinical trials
Targeted Biopsy of Carbon Nanoparticles Labelled Axillary Node for cN+ Breast Cancer

To explore the feasibility of target biopsy of carbon nanoparticles labelled lymph node after neoadjuvant systemic therapy for cN+ breast cancer, and evaluate whether it can accurately predict axillary lymph node status after neoadjuvant systemic therapy.

  • 0 views
  • 30 Jan, 2021
  • 1 location
Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

This phase III trial studies how well axillary reverse mapping works in preventing lymphedema in patients with breast cancer undergoing axillary lymph node dissection. Axillary reverse mapping

breast carcinoma
invasive breast cancer
isosulfan blue
lobular carcinoma in situ
breast surgery
  • 25 views
  • 16 Jun, 2021
  • 73 locations
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in …

ductal carcinoma
lumpectomy
carcinoma in situ
non-melanoma skin cancer
pertuzumab
  • 476 views
  • 16 Jun, 2021
  • 726 locations
Tailored AXIllary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS)

RATIONALE: The use of tailored axillary dissection as a tailored procedure will avoid surgical overtreatment by selectively removing the lymph nodes that are affected by the cancer, thereby sparing many women the unnecessary complications of a radical surgery, providing a better quality of life while keeping the same efficacy. PURPOSE: …

  • 9 views
  • 15 May, 2021
  • 92 locations
Nomogram to Predict Breast Cancer Related Lymphedema

It has been hypothesized that damaged arm lymphatic drainage is associated with the arm lymphedema after axillary lymph node dissection (ALND). However, the majority of breast cancer patients

  • 0 views
  • 27 Jan, 2021
  • 1 location
Identification and Preservation of Arm Lymphatics

Controversy in axillary reverse mapping in axillary lymph node dissection (ALND) possibly results from incomplete recognition of the arm lymphatic system (ALS) and its compromise to oncological

cancer
indocyanine green
mastectomy
axillary lymph node dissection
breast cancer
  • 0 views
  • 26 Jan, 2021
  • 1 location
Randomized Study of Elective Regional Lymph Node Irradiation in N1 Breast Cancer

This study evaluates the impact of elective regional lymph node irradiation on N1 breast cancer patients receiving post-lumpectomy radiotherapy and anthracycline plus taxane (AT)-based chemotherapy. We randomly assign patients having one to three metastatic lymph nodes (pN1) after breast-conserving surgery (BCS) and AT-based chemotherapy to undergo either whole-breast and regional …

invasive carcinoma
lumpectomy
immunostimulant
female breast cancer
breast-conserving surgery
  • 0 views
  • 11 Apr, 2021
  • 1 location
Hypofractionated LocoRegional Radiotherapy in Breast Cancer

The primary objective is to determine if hypofractionated radiotherapy (RT) delivered over 1 week to the breast and regional nodes (supraclavicular, axillary and internal mammary) following breast conserving surgery (BCS), or to the chest wall and regional nodes following mastectomy, is non-inferior to conventional fractionation delivered over 3 weeks in …

invasive carcinoma
cancer
mastectomy
breast cancer staging
breast-conserving surgery
  • 0 views
  • 12 Jun, 2021
  • 7 locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

lumpectomy
carcinoma in situ
targeted therapy
core needle biopsy
hepatitis b
  • 43 views
  • 10 May, 2021
  • 493 locations
Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

The aim of this study is to assess whether, omitting further axillary treatment (ALND and ART) for patients with early stage breast cancer and axillary nodal metastases on needle biopsy, who after NACT have no residual cancer in the lymph nodes on sentinel node biopsy, is non-inferior to axillary treatment …

progesterone
metastasis
breast cancer staging
HER2
sentinel lymph node biopsy
  • 0 views
  • 27 Jan, 2021
  • 2 locations