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Found 77 clinical trials
A Phase II, Open-Label Trial of Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Background Thymoma and thymic carcinoma are diseases of the thymus. Platinum-based chemotherapy is the standard treatment for these diseases. But in many cases, the disease returns after treatment. Researchers want to see if a new drug can help. Objective To see if bintrafusp alfa (M7824) is an effective treatment for …

  • 28 views
  • 25 Oct, 2022
  • 1 location
Phase I/II of NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Background Kaposi sarcoma (KS) tumors grow on the skin, lymph nodes, lungs, bone, and gastrointestinal tract. KS often affects people with immune deficiencies, such as among people living with HIV or those with prior history of transplant. Researchers want to see if 2 non-chemotherapy drugs can help people with KS. …

monoclonal antibodies
progressive disease
systemic chemotherapy
measurable disease
systemic therapy
  • 12 views
  • 22 Oct, 2022
  • 1 location
Real-world Evaluation of Efficacy and Safety With Avelumab (BAVENCIO®) + Axitinib (INLYTA®) in Patients With aRCC in Multiple EU Countries (AVION)

The main purpose of this study is to expand knowledge on the effectiveness of Avelumab intravenous infusion in combination with Axitinib as the first-line therapy in participants with advanced

carcinoma
cancer
axitinib
  • 0 views
  • 12 Oct, 2022
  • 46 locations
OBSERVATIONAL STUDY OF AVELUMAB AS FIRST-LINE MAINTENANCE TREATMENT OF PATIENTS WITH ADVANCED UROTHELIAL CANCER AFTER CHEMOTHERAPY

A MULTI-CENTRE NON-INTERVENTIONAL STUDY TO DESCRIBE THE EARLY CLINICAL EXPERIENCE OF AVELUMAB USED AS MONOTHERAPY FOR THE FIRST-LINE MAINTENANCE TREATMENT OF ADULT

  • 0 views
  • 04 Oct, 2022
  • 1 location
An Observational Chart Review Study To Describe The Real-World Outcomes And Use Of Avelumab In Combination With Axitinib For Treatment Of Patients With aRCC In The UK

An observational chart review study to describe the real-world outcomes and use of avelumab in combination with axitinib for treatment of patients with advanced renal cell carcinoma in the

  • 0 views
  • 06 Jun, 2022
  • 1 location
A NON-INTERVENTIONAL STUDY ON AVELUMAB USE IN PATIENTS WITH ADVANCED OR METASTATIC UROTHELIAL CARCINOMA (AVENANCE)

A multicenter ambispective (retrospective and prospective) non-interventional study of patients with locally advanced or metastatic urothelial carcinoma (adv/mUC) treated with avelumab in France

metastatic urothelial carcinoma
avelumab
platinum-based chemotherapy
  • 0 views
  • 12 Jul, 2022
  • 71 locations
A Study to Learn About First-line Avelumab Maintenance in Japanese Patients With Locally Advanced or Metastatic Urothelial Carcinoma

The purpose of this study is to learn about the current treatment patterns, safety, and effects of the study medicine(avelumab) for the treatment of urothelial carcinoma. This study is

metastatic urothelial carcinoma
avelumab
  • 0 views
  • 07 Oct, 2022
  • 1 location