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Found 81 clinical trials
Adjuvant Avelumab in Merkel Cell Cancer (ADAM)

This randomized phase III trial studies how well avelumab works in treating patients with Merkel cell cancer that has spread to the lymph nodes and have undergone surgery and/or radiation

  • 4 views
  • 17 Jun, 2022
  • 10 locations
mDCF + Avelumab in Resectable Esophago-gastric Adenocarcinoma (EGA)

carcinoma of the stomach, esophagogastric junction (EGJ), or lower third of the esophagus. Patients will receive neoadjuvant therapy consisting of 4 cycles of avelumab added to the modified

carcinoma
avelumab
metastasis
fluorouracil
direct bilirubin
  • 8 views
  • 01 Mar, 2022
  • 1 location
Avelumab With Valproic Acid in Virus-associated Cancer (LATENT)

immune system, therefore making the virus susceptible to attack by the immune system. In this study Valproic acid is being combined with an immune therapy, Avelumab. Avelumab is an antibody that targets

platelet count
carcinoma of cervix
cancer
estimated creatinine clearance
absolute neutrophil count
  • 16 views
  • 28 Feb, 2022
  • 1 location
Avelumab and Radiation in Muscle-Invasive Bladder Cancer

bladder. The drug in this study is: Avelumab (also known as BAVENCIO®)

carcinoma
avelumab
bladder cancer
bladder carcinoma
transurethral resection
  • 0 views
  • 03 May, 2022
  • 2 locations
Talazoparib and Avelumab in Participants With Metastatic Renal Cell Carcinoma

The purpose of this study is to see whether the combination of avelumab and talazoparib can be an effective treatment for metastatic renal cell carcinoma.

carcinoma
renal function
hysterectomy
cancer
ovarian suppression
  • 2 views
  • 23 Mar, 2022
  • 7 locations
Neoadjuvant AXITINIB and AVELUMAB for Patients With Localized Clear-cell RCC

a monocenter, open label, single arm, phase II study of the combination of axitinib with avelumab as neoadjuvant therapy in patients with intermediate to high-risk non-metastatic RCC

carcinoma
avelumab
renal function
axitinib
serum pregnancy test
  • 11 views
  • 03 Mar, 2022
  • 1 location
PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

This clinical study is aiming to determine the safest doses and schedule for the combination of two drugs named palbociclib and avelumab. The study will also be investigating how

palbociclib
progesterone
triple negative breast cancer
hysterectomy
hormone therapy
  • 1 views
  • 30 May, 2021
  • 1 location
Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer (ImmunoADAPT)

ratio. After 1 cycle (28 days) another biopsy will be obtained, and both arms will receive avelumab (A) for 3 additional cycles. Patients will then undergo breast surgery.

palbociclib
estrogen
tamoxifen
estrogen receptor
mammogram
  • 3 views
  • 30 Apr, 2022
  • 4 locations
A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors (REGOMUNE)

Assessment of the efficacy and safety of Regorafenib and Avelumab in patients with advanced or metastatic solid tumors (ten cohorts), once the Recommanded Phase II Dose (RP2D) has been

carcinoma
sarcoma
monoclonal antibodies
systemic therapy
cancer
  • 44 views
  • 04 Mar, 2022
  • 6 locations
Pemetrexed and Avelumab in Treating Patients With MTAP-Deficient Metastatic Urothelial Cancer

This phase II trial studies how well pemetrexed and avelumab work in treating patients with MTAP-deficient urothelial cancer that has spread to other places in the body. Pemetrexed may stop the

  • 7 views
  • 03 Feb, 2022
  • 1 location