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Found 15 clinical trials
VASCular Impact of Angiogenic Treatment in Patients With Advanced Colorectal Cancer

antiangiogens used in this indication is that of monoclonal antibodies, the leader of which is bevacizumab (Avastin, Roche, Bale, Switzerland). Bevacizumab works by inhibiting endothelial vascular growth factor

  • 0 views
  • 03 Apr, 2021
  • 1 location
Cultivated Autologous Oral Mucosal Epithelial Transplantation

Earlier protocol for cultivated oral mucosal epithelial transplantation (COMET) requires trypsin/EDTA to isolate epithelial cells from tissue, and uses murine 3T3 cells as feeder cells, which results in biosafety concern. This study uses collagenase instead of trypsin/EDTA to isolate epithelial cells, and does not use 3T3 cells co-culture, so as …

Accepts healthy volunteers
  • 24 views
  • 06 Feb, 2022
  • 1 location
A Trial to Compare the Efficacy, Safety, Pharmacokinetics and Immunogenecity of HD204 to Avastin® in Advanced Non-squamous Non-small Cell Lung Cancer Patients

In the SAMSON-2 study, the proposed biosimilar HD204 will be compared to its reference product EU-licensed Avastin. The aim of the study is to demonstrate equivalence of HD204 and EU-licensed

carboplatin
non-squamous non-small cell lung cancer
lung carcinoma
lung cancer
bevacizumab
  • 224 views
  • 19 Feb, 2022
  • 13 locations
A Study of HLX10 in Combination With Carboplatin Plus (+) Pemetrexed With or Without HLX04 Compared With Carboplatin+Pemetrexed in 1L Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

, which will evaluate the safety and efficacy of HLX10 in combination with carboplatin+pemetrexed with or without HLX04(biosimilar of avastin) compared with treatment with carboplatin+pemetrexed in 1st

administration intravenous
pemetrexed
carboplatin
ROS1
EGFR
  • 2 views
  • 13 May, 2022
  • 1 location
First Line Atezolizumab Paclitaxel and Bevacizumab (Avastin ) in mTNBC

(Avastin) in patients with advanced or metastatic triple-negative breast cancer (mTNBC)

  • 0 views
  • 27 Jan, 2021
  • 20 locations
Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

The high-grade malignant brain tumors, glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA), comprise the majority of all primary brain tumors in adults. This group of tumors also exhibits the most aggressive behavior, resulting in median overall survival durations of only 9-12 months for GBM, and 3-4 years for AA. Initial …

malignant glioma
beam radiation
brain tumor
primary brain neoplasm
oligoastrocytoma
  • 146 views
  • 05 Nov, 2021
  • 1 location
Super-Selective Intraarterial Intracranial Infusion of Bevacizumab (Avastin) for Glioblastoma Multiforme

The high-grade malignant brain tumor glioblastoma multiforme (GBM) comprise the majority of all primary brain tumors in adults. This group of tumors also exhibits the most aggressive behavior, resulting in median overall survival durations of only 9-12 months for GBM. Initial therapy consists of surgical resection, external beam radiation or …

complete resection
beam radiation
brain tumor
aptt
malignant brain tumor
  • 44 views
  • 12 Mar, 2021
  • 1 location
Bevacizumab in Ovarian Cancer Patients With Disease at Second-Look Surgery

The goal of this clinical research study is to learn if Avastin (bevacizumab) can help to control ovarian, fallopian, or primary peritoneal cancer that has been found during second-look surgery

fallopian tube
cancer of the ovary
primary peritoneal carcinoma
ct scan
bevacizumab
  • 8 views
  • 23 Mar, 2022
  • 1 location
An Interventional Study of Avastin (Bevacizumab) in Patients With Advanced/Metastatic Epithelial Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

This multicenter prospective study will evaluate the safety and efficacy of Avastin (bevacizumab) in routine clinical practice in patients with advanced/metastatic epithelial ovarian cancer

fallopian tube
ovarian epithelial carcinoma
cancer of the ovary
primary peritoneal carcinoma
stage iv ovarian epithelial cancer
  • 41 views
  • 11 May, 2022
  • 7 locations
The Sahlgrenska Anti-VEGF Study (SAHLVE)

The study investigates whether patients treated for neovascular (wet) age-related macular degeneration (AMD), with intravitreal injection with bevacizumab (Avastin) after two years need more

  • 0 views
  • 11 May, 2022
  • 1 location