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Found 142 clinical trials
A Phase I Study of Bendamustine and Melphalan Conditioning and Autologous Stem Cell Transplantation for Treatment of Multiple Myeloma and Relapsed/Refractory B-cell Lymphoma in Elderly Patients

This study is testing a combination of chemo-immuno therapy called RBM. RBM consists of combination of drugs: rituximab, bendamustine, and melphalan followed by reinfusion of the participants own stem cells which is called autologous stem cell transplant (ASCT). Compared to the standard BEAM regimen, this RBM regimen may or may …

rituximab
cell transplantation
carbon monoxide
diffuse large b-cell lymphoma
hodgkin's disease
  • 3 views
  • 12 Mar, 2022
  • 1 location
  • 0 views
  • 06 May, 2022
  • 16 locations
A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease (PRECIZN-1)

autologous hematopoietic stem cell transplantation using BIVV003.

asthma
sickle hemoglobin
cell transplantation
acute chest syndrome
apheresis
  • 15 views
  • 24 Apr, 2022
  • 6 locations
A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease (PRECIZN-1)

autologous hematopoietic stem cell transplantation using BIVV003.

asthma
sickle hemoglobin
cell transplantation
acute chest syndrome
apheresis
  • 23 views
  • 08 Apr, 2022
  • 5 locations
ASCT With Nivolumab in Patients With Multiple Myeloma

This is an open-label, single center trial of Autologous Stem Cell Transplantation (ASCT) with nivolumab in multiple myeloma patients to determine the efficacy and safety of ASCT and PD1

granulocyte colony stimulating factor
cell transplantation
measurable disease
colony stimulating factor
induction therapy
  • 3 views
  • 25 Apr, 2022
  • 1 location
Precision Dosing of Busulfan in Children Undergoing HSCT

The objective of this clinical trial is to evaluate the personalization the conditioning regimen prior to the hematopoietic stem cell transplant (HSCT) in children and adolescents, to improve HSCT efficacy while reducing conditioning-related toxicities. Namely, we are going to compare the accuracy of two methods for determining the first dose …

  • 0 views
  • 11 Aug, 2021
  • 1 location
  • 1 views
  • 25 Jan, 2021
  • 1 location
Maintenance Therapy Post-HSCT in High-risk Aggressive Lymphoma

Relapse after autologous hematopoietic stem cell transplantation (ASCT) is still challenging for high-risk aggressive lymphoma. This study was to investigate the efficacy and safety of

  • 2 views
  • 14 Feb, 2022
  • 1 location
Brentuximab Vedotin and BeEAM High-dose Chemotherapy in Lymphomas (BAL)

) before autologous stem cell transplantation in CD30+ malignant lymphomas.

cell transplantation
autologous hematopoietic stem cell transplant
t-cell lymphoma
lymphoma
remission
  • 4 views
  • 10 Mar, 2022
  • 1 location
Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)

This is a phase II interventional study evaluating the use of minimal residual disease by next generation sequencing to defer autologous hematopoietic stem cell transplantation (AHCT) in

hypercalcemia
dexamethasone
cell transplantation
measurable disease
bortezomib
  • 0 views
  • 30 Oct, 2021
  • 1 location